Evidence map›Paper›PMID 38404353›Full record

ArticleBiomedical optics express2024

Hybrid heterogeneous phantoms for biomedical applications: a demonstration to dosimetry validation.

M Daniyal Ghauri, Stefan Šušnjar, Claudia Nunzia Guadagno, Somdatta Bhattacharya, Björn Thomasson, Johannes Swartling, Rekha Gautam, Stefan Andersson-Engels, Sanathana Konugolu Venkata Sekar

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

M Daniyal GhauriTyndall National Institute, Lee Maltings Complex, Dyke Parade, T12R5CP, Cork, Ireland.ORCID https://orcid.org/0000-0001-7667-7702
Stefan ŠušnjarSpectraCure AB, Gasverksgatan 1, SE-222 29 Lund, Sweden.ORCID https://orcid.org/0000-0001-7925-0624
Claudia Nunzia GuadagnoBioPixS Ltd - Biophotonics Standards, IPIC, Lee Maltings Complex, Dyke Parade, T12R5CP, Cork, Ireland.
Somdatta BhattacharyaTyndall National Institute, Lee Maltings Complex, Dyke Parade, T12R5CP, Cork, Ireland.
Björn ThomassonSpectraCure AB, Gasverksgatan 1, SE-222 29 Lund, Sweden.
Johannes SwartlingSpectraCure AB, Gasverksgatan 1, SE-222 29 Lund, Sweden.
Rekha GautamTyndall National Institute, Lee Maltings Complex, Dyke Parade, T12R5CP, Cork, Ireland.ORCID https://orcid.org/0000-0002-1176-8491
Stefan Andersson-EngelsTyndall National Institute, Lee Maltings Complex, Dyke Parade, T12R5CP, Cork, Ireland.ORCID https://orcid.org/0000-0001-5640-3122
Sanathana Konugolu Venkata SekarTyndall National Institute, Lee Maltings Complex, Dyke Parade, T12R5CP, Cork, Ireland.ORCID https://orcid.org/0000-0003-0912-1282
SpectraCure (Sweden) · SEUniversity College Cork · IELund University · SEStandard Bio (Norway) · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phantoms simultaneously mimicking anatomical and optical properties of real tissues can play a pivotal role for improving dosimetry algorithms. The aim of the paper is to design and develop a hybrid phantom model that builds up on the strengths of solid and liquid phantoms for mimicking various anatomical structures for prostate cancer photodynamic therapy (PDT) dosimetry validation. The model comprises of a photosensitizer-embedded gelatin lesion within a liquid Intralipid prostate shape that is surrounded by a solid silicone outer shell. The hybrid phantom was well characterized for optical properties. The final assembled phantom was also evaluated for fluorescence tomographic reconstruction in conjunction with SpectraCure's IDOSE software. The developed model can lead to advancements in dosimetric evaluations. This would improve PDT outlook as a clinical treatment modality and boost phantom based standardization of biophotonic devices globally.

Identifiers

PMID38404353
PMCPMC10890852
OpenAlexW4390812181

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.