Evidence map›Paper›PMID 38404668›Full record

ArticleFrontiers in genetics2024

Comprehensive transcriptomic analysis unveils the interplay of mRNA and LncRNA expression in shaping collagen organization and skin development in Dezhou donkeys.

Xinrui Wang, Yongdong Peng, Huili Liang, Muhammad Zahoor Khan, Wei Ren, Bingjian Huang, Yinghui Chen, Shishuai Xing, Yandong Zhan, Changfa Wang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in genetics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Overview of Donkey Welfare and Husbandry Practices in Asia.Animals : an open access journal from MDPI · 2025
    Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Application of Omics in Donkey Meat Research: A Review.Animals : an open access journal from MDPI · 2025
    Review
  10. Review
  11. Unraveling the genetic and physiological potential of donkeys: insights from genomics, proteomics, and metabolomics approaches.Mammalian genome : official journal of the International Mammalian Genome Society · 2025
    Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Xinrui WangLiaocheng Research Institute of Donkey High-Efficiency Breeding, Liaocheng University, Liaocheng, China.
Yongdong PengLiaocheng Research Institute of Donkey High-Efficiency Breeding, Liaocheng University, Liaocheng, China.
Huili LiangLiaocheng Research Institute of Donkey High-Efficiency Breeding, Liaocheng University, Liaocheng, China.
Muhammad Zahoor KhanLiaocheng Research Institute of Donkey High-Efficiency Breeding, Liaocheng University, Liaocheng, China.
Wei RenLiaocheng Research Institute of Donkey High-Efficiency Breeding, Liaocheng University, Liaocheng, China.
Bingjian HuangLiaocheng Research Institute of Donkey High-Efficiency Breeding, Liaocheng University, Liaocheng, China.
Yinghui ChenLiaocheng Research Institute of Donkey High-Efficiency Breeding, Liaocheng University, Liaocheng, China.
Shishuai XingLiaocheng Research Institute of Donkey High-Efficiency Breeding, Liaocheng University, Liaocheng, China.
Yandong ZhanLiaocheng Research Institute of Donkey High-Efficiency Breeding, Liaocheng University, Liaocheng, China.
Changfa WangLiaocheng Research Institute of Donkey High-Efficiency Breeding, Liaocheng University, Liaocheng, China.
Liaocheng University · CNUniversidade Federal dos Vales do Jequitinhonha e Mucuri · BRChinese Academy of Agricultural Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The primary focus of donkey hide gelatin processing lies in the dermal layer of donkey hide due to its abundant collagen content. However, the molecular mechanism involved in collagen organization and skin development in donkey skin tissue across various developmental stages remains incomplete. The current study aims to investigate the transcriptomic screening of lncRNAs and mRNA associated with skin development and collagen organization across different ages in Dezhou donkeys' skin. In the pursuit of this objective, we used nine skin tissue samples obtained from Dezhou donkeys at various ages including 8-month fetal stage, followed by 2 and 8 years. RNA-seq analysis was performed for the transcriptomic profiling of differentially expressed genes (DEGs) and lncRNAs associated with skin development in different age groups. Our investigation revealed the presence of 6,582, 6,455, and 405 differentially expressed genes and 654, 789, and 29 differentially expressed LncRNAs within the skin tissues of Dezhou donkeys when comparing young donkeys (YD) vs. middle-aged donkeys (MD), YD vs. old donkeys (OD), and MD vs. OD, respectively. Furthermore, we identified

Indexed as

collagenDezhou donkeygenetic markershide gelatinKEGGlncRNAmRNARNA-seq

Identifiers

PMID38404668
PMCPMC10884126
OpenAlexW4391690731

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.