Evidence map›Paper›PMID 38407039›Full record

ArticleJournal of proteome research2024

Quantitative Metabolomics and Lipoprotein Analysis of PDAC Patients Suggests Serum Marker Categories for Pancreatic Function, Pancreatectomy, Cancer Metabolism, and Systemic Disturbances.

Gyuntae Bae, Georgy Berezhnoy, Alejandra Flores, Claire Cannet, Hartmut Schäfer, Marc H Dahlke, Patrick Michl, Markus W Löffler, Alfred Königsrainer, Christoph Trautwein

Open access · greenAbstract read
In one paragraph

Article in Journal of proteome research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Gyuntae BaeWerner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, University Hospital Tübingen, Tübingen 72076, Germany.
Georgy BerezhnoyWerner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, University Hospital Tübingen, Tübingen 72076, Germany.
Alejandra FloresWerner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, University Hospital Tübingen, Tübingen 72076, Germany.
Claire CannetBruker BioSpin GmbH & Co. KG, BioPharma and Applied Division, Ettlingen 76275, Germany.
Hartmut SchäferBruker BioSpin GmbH & Co. KG, BioPharma and Applied Division, Ettlingen 76275, Germany.
Marc H DahlkeDepartment of General and Visceral Surgery, Robert-Bosch-Krankenhaus, Stuttgart 70376, Germany.
Patrick MichlDept of Internal Medicine IV, University Hospital Heidelberg, Heidelberg 69120, Germany.
Markus W LöfflerDepartment of General, Visceral and Transplant Surgery, University Hospital Tübingen, Tübingen 72076, Germany.
Alfred KönigsrainerDepartment of General, Visceral and Transplant Surgery, University Hospital Tübingen, Tübingen 72076, Germany.
Christoph TrautweinWerner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, University Hospital Tübingen, Tübingen 72076, Germany.ORCID 0000-0003-4672-6395
Siemens (Germany) · DEBruker (United States) · USGerman Cancer Research Center · DEHeidelberg University · DERobert Bosch Hospital · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic ductal adenocarcinoma (PDAC) is difficult to diagnose in the early stages and lacks reliable biomarkers. The scope of this project was to establish quantitative nuclear magnetic resonance (NMR) spectroscopy to comprehensively study blood serum alterations in PDAC patients. Serum samples from 34 PDAC patients obtained before and after pancreatectomy as well as 83 age- and sex-matched control samples from healthy donors were analyzed with

Indexed as

Carcinoma, Pancreatic DuctalPancreatic NeoplasmsBiomarkers, TumorHumansMetabolomicsPancreatectomyBiomarkers, Tumor2-hydroxybutyratediabetesglucagonglucose intolerancegut microbiomeinflammationinsulin resistancelipaseoncologypancreatic cancer

Identifiers

PMID38407039
PMCPMC11003419
OpenAlexW4392156132

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.