Evidence mapPaperPMID 38407563Full record

SynthesisPharmacology research & perspectives2024

Progress in the treatment of diabetic cardiomyopathy, a systematic review.

Yiyi Shou, Xingyu Li, Quan Fang, Aqiong Xie, Yinghong Zhang, Xinyan Fu, Mingwei Wang, Wenyan Gong, Xingwei Zhang, Dong Yang

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Pharmacology research & perspectives, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
8.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Yiyi ShouDepartment of Clinical Medicine, Affiliated Hospital of Hangzhou Normal University, Hangzhou Normal University, Hangzhou, China.ORCID https://orcid.org/0009-0002-5716-1609
Xingyu LiDepartment of Clinical Medicine, Affiliated Hospital of Hangzhou Normal University, Hangzhou Normal University, Hangzhou, China.ORCID https://orcid.org/0009-0002-5578-4693
Quan FangDepartment of Clinical Medicine, Affiliated Hospital of Hangzhou Normal University, Hangzhou Normal University, Hangzhou, China.ORCID https://orcid.org/0009-0005-7135-5583
Aqiong XieDepartment of Clinical Medicine, Affiliated Hospital of Hangzhou Normal University, Hangzhou Normal University, Hangzhou, China.ORCID https://orcid.org/0009-0002-1168-7787
Yinghong ZhangDepartment of Immunology, Affiliated Hospital of Hangzhou Normal University, Hangzhou, China.ORCID https://orcid.org/0000-0001-6805-7917
Xinyan FuDepartment of Cardiology, Affiliated Hospital of Hangzhou Normal University, Hangzhou, China.ORCID https://orcid.org/0000-0002-0918-5924
Mingwei WangDepartment of Cardiology, Affiliated Hospital of Hangzhou Normal University, Hangzhou, China.ORCID https://orcid.org/0000-0001-9060-5107
Wenyan GongDepartment of Clinical Medicine, Affiliated Hospital of Hangzhou Normal University, Hangzhou Normal University, Hangzhou, China.ORCID https://orcid.org/0000-0001-6950-7545
Xingwei ZhangDepartment of Clinical Medicine, Affiliated Hospital of Hangzhou Normal University, Hangzhou Normal University, Hangzhou, China.ORCID https://orcid.org/0000-0003-2985-8177
Dong YangDepartment of Clinical Medicine, Affiliated Hospital of Hangzhou Normal University, Hangzhou Normal University, Hangzhou, China.ORCID https://orcid.org/0000-0002-8894-8976
Affiliated Hospital of Hangzhou Normal University · CN

Funding

National Natural Science Foundation of China 81900745Natural Science Foundation of Zhejiang Province LY24H310005
6 · The paper itself

Abstract

Diabetic cardiomyopathy (DCM) is a condition characterized by myocardial dysfunction that occurs in individuals with diabetes, in the absence of coronary artery disease, valve disease, and other conventional cardiovascular risk factors such as hypertension and dyslipidemia. It is considered a significant and consequential complication of diabetes in the field of cardiovascular medicine. The primary pathological manifestations include myocardial hypertrophy, myocardial fibrosis, and impaired ventricular function, which can lead to widespread myocardial necrosis. Ultimately, this can progress to the development of heart failure, arrhythmias, and cardiogenic shock, with severe cases even resulting in sudden cardiac death. Despite several decades of both fundamental and clinical research conducted globally, there are currently no specific targeted therapies available for DCM in clinical practice, and the incidence and mortality rates of heart failure remain persistently high. Thus, this article provides an overview of the current treatment modalities and novel techniques pertaining to DCM, aiming to offer valuable insights and support to researchers dedicated to investigating this complex condition.

Indexed as

Diabetic CardiomyopathiesHeart FailureHumansdiabetic cardiomyopathyheart failuremyocardial fibrosispharmacotherapytype 2 diabetes mellitus

Identifiers

PMID38407563
PMCPMC10895687
OpenAlexW4392183093

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.