Evidence map›Paper›PMID 38408804›Full record

ReviewVitamins and hormones2024

Serotonin and the serotonin transporter in the adrenal gland.

Mary Beth Bauer, Kevin P M Currie

Open access · greenAbstract readReview
In one paragraph

Review in Vitamins and hormones, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Trial
  2. Adrenal adenoma mimicking angiomyolipoma: A diagnostic pitfall.The Journal of international medical research · 2026
    Article
  3. A Comprehensive 4-layeredCurrent pharmaceutical biotechnology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Mary Beth BauerDepartment of Biomedical Sciences, Cooper Medical School of Rowan University, South Broadway, Camden, NJ, United States.
Kevin P M CurrieDepartment of Biomedical Sciences, Cooper Medical School of Rowan University, South Broadway, Camden, NJ, United States. Electronic address: Currie@rowan.edu.
Cooper Medical School of Rowan University · US

Funding

Serotonergic control of the sympathoadrenal stress responseR15NS132585 · NINDS · ROWAN UNIVERSITY · PI CURRIE, KEVIN P · 2023 to 2023
$483k
NINDS NIH HHS R15 NS132585
6 · The paper itself

Abstract

The adrenal glands are key components of the mammalian endocrine system, helping maintain physiological homeostasis and the coordinated response to stress. Each adrenal gland has two morphologically and functionally distinct regions, the outer cortex and inner medulla. The cortex is organized into three concentric zones which secrete steroid hormones, including aldosterone and cortisol. Neural crest-derived chromaffin cells in the medulla are innervated by preganglionic sympathetic neurons and secrete catecholamines (epinephrine, norepinephrine) and neuropeptides into the bloodstream, thereby functioning as the neuroendocrine arm of the sympathetic nervous system. In this article we review serotonin (5-HT) and the serotonin transporter (SERT; SLC6A4) in the adrenal gland. In the adrenal cortex, 5-HT, primarily sourced from resident mast cells, acts as a paracrine signal to stimulate aldosterone and cortisol secretion through 5-HT

Indexed as

SerotoninSerotonin Plasma Membrane Transport ProteinsAdrenal GlandsAldosteroneAnimalsHumansHydrocortisoneMammalsAldosteroneHydrocortisoneSerotoninSerotonin Plasma Membrane Transport ProteinsSLC6A4 protein, humanAdrenal cortexAdrenal medullaCatecholamineChromaffinG protein coupled receptorSerotoninSerotonin transporterSerotonylationStressSympathetic nervous system

Identifiers

PMID38408804
PMCPMC11217909
OpenAlexW4384788504

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.