Evidence map›Paper›PMID 38410094›Full record

ArticleClinical optometry2024

Alteration Ocular Motility in Retinitis Pigmentosa: Case-Control Study.

Anna Maria Comberiati, Chiara Lomartire, Mariaelena Malvasi, Raffaele Migliorini, Fernanda Pacella, Vito Maurizio Malvasi, Paolo Turchetti, Elena Pacella

Open access · goldAbstract read
In one paragraph

Article in Clinical optometry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Anna Maria ComberiatiDepartment of Sense Organs, Sapienza University of Rome, Rome, Italy.
Chiara LomartireDepartment of Sense Organs, Sapienza University of Rome, Rome, Italy.
Mariaelena MalvasiDepartment of Sense Organs, Sapienza University of Rome, Rome, Italy.
Raffaele MiglioriniDepartment of Sense Organs, Sapienza University of Rome, Rome, Italy.
Fernanda PacellaDepartment of Ophthalmology, Carlo Poma Hospital, Mantua, Italy.ORCID 0000-0002-3649-5805
Vito Maurizio MalvasiDepartment of Odontostomatological and Maxillo-Facial Sciences, Sapienza University of Rome, Rome, Italy.
Paolo TurchettiNational Institute for Health, Migration and Poverty (INMP/NIHMP), Rome, Italy.
Elena PacellaDepartment of Sense Organs, Sapienza University of Rome, Rome, Italy.ORCID 0000-0002-5431-6399
Sapienza University of Rome · ITAzienda Ospedaliera Carlo Poma · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To evaluate ocular motility (OM) disorders and strabismus in a sample of patients with retinitis pigmentosa (RP) and a control sample. Methods: In this cross-sectional retrospective analysis, we studied a sample of RP patients with a mean age of 48.74 years and an average visual acuity of 7/10 based on Snellen optotype and a sample of control patients with similar mean age (49 years [men], 47 years [women]) and sex and an average visual acuity of 9.9/10, with the aim of assessing correlations between alteration of OM and strabismus in RP patients based on age, high refractive defect, or severely impaired binocular vision. The examination followed a protocol of testing for anamnesis and best-corrected visual acuity, as well as a complete eye examination, corneal reflex, cover test, OM, Hess screen, and Lang test. Results: At the first orthoptic evaluation, 45.16% of patients showed strabismus, 41.93% exotropia (25% of cases intermittent), 3.22% esotropia, and 6.45% vertical deviation. Later evaluation showed strabismus in 25.80% of patients, exotropia in 19.35% (9.67% intermittent), esotropia in 3.22%, and vertical deviation in 3.22%. Assessment of eye motility study showed 51.6% overaction of the inferior oblique and hypofunction of the superior rectus, and 18% overaction of the lateral rectus and hypofunction of the medial rectus. According to our results, alterations in OM and strabismus in RP patients are not correlated with age or high refractive defect. Therefore, motility disorders and strabismus are attributed to a genetic factor to which men are more susceptible. Conclusion: The incidence of OM disorder was 77.42%, and strabismus was present in 45.16% of patients.

Indexed as

genetic factorocular motilityorthoptic evaluationretinitis pigmentosastrabismus

Identifiers

PMID38410094
PMCPMC10895995
OpenAlexW4392005326

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.