Evidence map›Paper›PMID 38410921›Full record

ReviewJournal of materials chemistry. B2024

Trends in bioactivity: inducing and detecting mineralization of regenerative polymeric scaffolds.

Brandon M Nitschke, Felipe O Beltran, Mariah S Hahn, Melissa A Grunlan

Abstract readReview
In one paragraph

Review in Journal of materials chemistry. B, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. iScience · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Brandon M NitschkeDepartment of Biomedical Engineering, Texas A&M University, College Station, TX 77843, USA. mgrunlan@tamu.edu.ORCID 0009-0007-8463-210X
Felipe O BeltranDepartment of Materials Science & Engineering, Texas A&M University, College Station, TX 77843, USA.
Mariah S HahnDepartment of Biomedical Engineering, Rensselaer Polytechnic Institute, Troy, NY 12180, USA.
Melissa A GrunlanDepartment of Biomedical Engineering, Texas A&M University, College Station, TX 77843, USA. mgrunlan@tamu.edu.ORCID 0000-0002-5428-0461

Funding

Bioactive, "Self-fitting" Shape Memory Polymer (SMP) Scaffolds to Treat Cranial Bone DefectsR01DE025886 · NIDCR · TEXAS ENGINEERING EXPERIMENT STATION · PI GRUNLAN, MELISSA · 2017 to 2020
$1.8M
NIDCR NIH HHS R01 DE025886
6 · The paper itself

Abstract

Due to limitations of biological and alloplastic grafts, regenerative engineering has emerged as a promising alternative to treat bone defects. Bioactive polymeric scaffolds are an integral part of such an approach. Bioactivity importantly induces hydroxyapatite mineralization that promotes osteoinductivity and osseointegration with surrounding bone tissue. Strategies to confer bioactivity to polymeric scaffolds utilize bioceramic fillers, coatings and surface treatments, and additives. These approaches can also favorably impact mechanical and degradation properties. A variety of fabrication methods are utilized to prepare scaffolds with requisite morphological features. The bioactivity of scaffolds may be evaluated with a broad set of techniques, including

Indexed as

PolymersTissue ScaffoldsBone and BonesDurapatiteDurapatitePolymers

Identifiers

PMID38410921
PMCPMC10935659

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.