Evidence map›Paper›PMID 38414752›Full record

ArticleFrontiers in cellular neuroscience2024

Role of a Pdlim5:PalmD complex in directing dendrite morphology.

Yogesh Srivastava, Maxsam Donta, Lydia L Mireles, Adriana Paulucci-Holthauzen, M Neal Waxham, Pierre D McCrea

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Exploring the PDZ, DUF, and LIM Domains of Pdlim5 in Dendrite Branching.International journal of molecular sciences · 2024
    Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yogesh SrivastavaDepartment of Genetics, University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Maxsam DontaDepartment of Genetics, University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Lydia L MirelesDepartment of Neurobiology and Anatomy, UTHealth, Houston, TX, United States.
Adriana Paulucci-HolthauzenDepartment of Genetics, University of Texas MD Anderson Cancer Center, Houston, TX, United States.
M Neal WaxhamDepartment of Neurobiology and Anatomy, UTHealth, Houston, TX, United States.
Pierre D McCreaDepartment of Genetics, University of Texas MD Anderson Cancer Center, Houston, TX, United States.
The University of Texas MD Anderson Cancer Center · USThe University of Texas Health Science Center at Houston · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI DIANE BODURKA · 1985 to 2026
$290.8M
A phospho-switch in delta-catenin: relationship to PDZ-domain proteins and neuron developmentR01MH115717 · NIMH · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI MCCREA, PIERRE D · 2018 to 2022
$2.4M
Upgrading an existing NIKON A1-confocal with LUNV Laser Launch and DU-G detectorS10OD024976 · OD · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI LOZANO, GUILLERMINA · 2018 to 2018
$202k
NCI NIH HHS P30 CA016672NIH HHS S10 OD024976NIMH NIH HHS R01 MH115717
6 · The paper itself

Abstract

Neuronal connectivity is regulated during normal brain development with the arrangement of spines and synapses being dependent on the morphology of dendrites. Further, in multiple neurodevelopmental and aging disorders, disruptions of dendrite formation or shaping is associated with atypical neuronal connectivity. We showed previously that Pdlim5 binds delta-catenin and promotes dendrite branching. We report here that Pdlim5 interacts with PalmD, a protein previously suggested by others to interact with the cytoskeleton (e.g.,

Indexed as

catenincytoskeletondendritemorphologyneuronshape

Identifiers

PMID38414752
PMCPMC10896979
OpenAlexW4391784584

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.