Evidence map›Paper›PMID 38415356›Full record

ArticleCirculation. Arrhythmia and electrophysiology2024

Nelson A Rodríguez, Nihir Patel, Rafael Dariolli, Simon Ng, Angelika G Aleman, Jingqi Q X Gong, Hung-Mo Lin, Matthew Rodríguez, Rebecca Josowitz, Katia Sol-Church and 6 more

Open access · greenAbstract read
In one paragraph

Article in Circulation. Arrhythmia and electrophysiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 8 institutions in 2 countries.

Nelson A RodríguezMindich Child Health & Development Institute (N.A.R., N.P., S.N., A.G.A., M.R., B.D.G.), Icahn School of Medicine at Mount Sinai, New York, NY.ORCID 0000-0003-4757-379X
Nihir PatelMindich Child Health & Development Institute (N.A.R., N.P., S.N., A.G.A., M.R., B.D.G.), Icahn School of Medicine at Mount Sinai, New York, NY.ORCID 0000-0002-4253-3097
Rafael DariolliDepartment of Pharmacological Sciences & Systems Biology Center New York (R.D., J.Q.X.G., E.A.S.), Icahn School of Medicine at Mount Sinai, New York, NY.ORCID 0000-0003-0957-1259
Simon NgMindich Child Health & Development Institute (N.A.R., N.P., S.N., A.G.A., M.R., B.D.G.), Icahn School of Medicine at Mount Sinai, New York, NY.
Angelika G AlemanMindich Child Health & Development Institute (N.A.R., N.P., S.N., A.G.A., M.R., B.D.G.), Icahn School of Medicine at Mount Sinai, New York, NY.ORCID 0000-0002-5518-6450
Jingqi Q X GongDepartment of Pharmacological Sciences & Systems Biology Center New York (R.D., J.Q.X.G., E.A.S.), Icahn School of Medicine at Mount Sinai, New York, NY.ORCID 0000-0002-7401-0119
Hung-Mo LinYale Center for Analytical Sciences (YCAS), New Haven, CT (H.-M.L.).ORCID 0000-0003-3176-6570
Matthew RodríguezMindich Child Health & Development Institute (N.A.R., N.P., S.N., A.G.A., M.R., B.D.G.), Icahn School of Medicine at Mount Sinai, New York, NY.ORCID 0009-0008-0871-9892
Rebecca JosowitzDivision of Cardiology, Children's Hospital of Philadelphia, Philadelphia, PA (R.J.).ORCID 0009-0006-4106-589X
Katia Sol-ChurchDepartment of Pathology, University of Virginia School of Medicine, Charlottesville, VA (K.S.-C.).
Karen W GrippDivision of Medical Genetics; Al duPont Hospital for Children/Nemours, Wilmington, DE (K.W.G.).ORCID 0000-0001-8200-1733
Xianming LinLeon H. Charney Division of Cardiology, New York University School of Medicine (X.L., G.I.F.).ORCID 0000-0002-3638-8137
Soomin C SongIon Lab, Department of Pathology, NYU Langone Health, New York, NY (S.C.S.).
Glenn I FishmanLeon H. Charney Division of Cardiology, New York University School of Medicine (X.L., G.I.F.).ORCID 0000-0002-2366-8527
Eric A SobieDepartment of Pharmacological Sciences & Systems Biology Center New York (R.D., J.Q.X.G., E.A.S.), Icahn School of Medicine at Mount Sinai, New York, NY.ORCID 0000-0001-7327-8538
Bruce D GelbMindich Child Health & Development Institute (N.A.R., N.P., S.N., A.G.A., M.R., B.D.G.), Icahn School of Medicine at Mount Sinai, New York, NY.ORCID 0000-0001-8527-5027
Child Health and Development Institute · USIcahn School of Medicine at Mount Sinai · USLondon Borough of Hackney · GBAlfred I. duPont Hospital for Children · USChildren's Hospital of Philadelphia · USNYU Langone Health · USUniversity of Virginia · USYale Cancer Center · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
TRAINING PROGRAM IN MOLECULAR AND CELLULAR CARDIOLOGYT32HL007824 · NHLBI · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI GELB, BRUCE D · 1995 to 2022
$8.6M
Pediatric Heart Disease: Getting from Mutations to TherapeuticsR35HL135742 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI GELB, BRUCE D · 2017 to 2023
$6.1M
Purkinje Cells and Arrhythmia MechanismsR01HL105983 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI FISHMAN, GLENN I · 2011 to 2019
$5.2M
Transcriptional regulation in the ventricular conduction systemR01HL146107 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI FISHMAN, GLENN I, MAASS, KAREN · 2019 to 2022
$3.0M
Big Omics Data Engine 2 SupercomputerS10OD026880 · OD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KOVATCH, PATRICIA · 2019 to 2019
$2.0M
Transforming Genomics with 5 PB Big Omics Data Engine Cray CS300-AC SupercomputerS10OD018522 · OD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KOVATCH, PATRICIA · 2014 to 2014
$1.9M
Human Induced Pluripotent Cell Models of Pediatric Cardiac DisordersR01HL113499 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI GELB, BRUCE D · 2013 to 2016
$1.9M
Automated Patch Clamp SystemS10OD034378 · OD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SONG, SOOMIN CHRISTOPHER · 2024 to 2024
$625k
NCATS NIH HHS UL1 TR001863NHLBI NIH HHS R01 HL105983NHLBI NIH HHS R01 HL113499NHLBI NIH HHS R01 HL146107NHLBI NIH HHS R35 HL135742NHLBI NIH HHS T32 HL007824NIH HHS S10 OD018522NIH HHS S10 OD026880NIH HHS S10 OD034378
6 · The paper itself

Abstract

backgroundGermline

methods

resultsACMs harboring

conclusionsCS-associated gain-of-function

Indexed as

Induced Pluripotent Stem CellsMyocytes, CardiacAction PotentialsCalciumCalcium ChannelsCell DifferentiationChild, PreschoolHeart AtriaHumansProto-Oncogene Proteins p21(ras)TachycardiaCalciumCalcium ChannelsHRAS protein, humanProto-Oncogene Proteins p21(ras)Costello syndromeheart ratehumaninduced pluripotent stem cellstachycardia

Identifiers

PMID38415356
PMCPMC11021157
OpenAlexW4392238059

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.