Evidence map›Paper›PMID 38416230›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2024

Experiences of treatment decision-making among older newly diagnosed adults with acute myeloid leukemia: a qualitative descriptive study.

Daniel R Richardson, Carl J Mhina, Randall Teal, Amy C Cole, Karthik Adapa, Ashley L Bryant, Norah Crossnohere, Stephanie C Wheeler, John F P Bridges, William A Wood

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In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
3.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Daniel R RichardsonUNC Lineberger Comprehensive Cancer Center, Chapel Hill, NC, USA. daniel_richardson@med.unc.edu.
Carl J MhinaUniversity of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Randall TealUNC Lineberger Comprehensive Cancer Center, Chapel Hill, NC, USA.
Amy C ColeUniversity of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Karthik AdapaUniversity of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Ashley L BryantUNC Lineberger Comprehensive Cancer Center, Chapel Hill, NC, USA.
Norah CrossnohereThe Ohio State University, Columbus, OH, USA.
Stephanie C WheelerUniversity of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
John F P BridgesThe Ohio State University, Columbus, OH, USA.
William A WoodUNC Lineberger Comprehensive Cancer Center, Chapel Hill, NC, USA.
University of North Carolina at Chapel Hill · USUNC Lineberger Comprehensive Cancer CenterThe Ohio State University · US

Funding

NIH HHS 1L30CA264755-01
6 · The paper itself

Abstract

purposeTreatment decision-making for older adults with acute myeloid leukemia (AML) is complex and preference-sensitive. We sought to understand the patient experience of treatment decision-making to identify specific challenges in shared decision-making to improve clinical care and to inform the development of directed interventions.

methodsWe conducted in-depth interviews with newly diagnosed older (≥ 60 years) adults with AML and their caregivers following a semi-structured interview guide at a public safety net academic hospital. Interviews were digitally recorded, and qualitative thematic analysis was employed to synthesize findings.

resultsEighteen in-depth interviews were conducted. Age ranged from 62 to 78 years. Patients received intermediate- (50%) or high-intensity (44%) chemotherapy or best supportive care only (6%). Six themes of patient experiences emerged from the analysis: patients (1) felt overwhelmed and in shock at diagnosis, (2) felt powerless to make decisions, (3) felt rushed and unprepared to make a treatment decision, (4) desired to follow oncologist recommendations for treatment, (5) balanced multiple competing factors during treatment decision-making, and (6) desired for ongoing engagement into their care planning. Patients reported many treatment outcomes that were important in treatment decision-making.

conclusionsOlder adults with newly diagnosed AML feel devastated and in shock at their diagnosis which appears to contribute to a feeling of being overwhelmed, unprepared, and rushed into treatment decisions. Because no one factor dominated treatment decision-making for all patients, the use of strategies to elicit individual patient preferences is critical to inform treatment decisions. Interventions are needed to reduce distress and increase a sense of participation in treatment decision-making.

Indexed as

Leukemia, Myeloid, AcuteOncologistsAgedDecision Making, SharedEmotionsHumansMiddle AgedPatient PreferenceAcute myeloid leukemiaClinical careTreatment decision-making

Identifiers

PMID38416230
OpenAlexW4392235019

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.