Evidence map›Paper›PMID 38416825›Full record

ArticleScience advances2024

N-MYC regulates cell survival via eIF4G1 in inv(16) acute myeloid leukemia.

Philomina Sona Peramangalam, Sridevi Surapally, Anthony J Veltri, Shikan Zheng, Robert Burns, Nan Zhu, Sridhar Rao, Carsten Muller-Tidow, John H Bushweller, John A Pulikkan

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Philomina Sona PeramangalamProgram in Stem Cell Biology and Hematopoiesis, Versiti Blood Research Institute, Milwaukee, WI, USA.ORCID 0009-0008-7824-3391
Sridevi SurapallyProgram in Stem Cell Biology and Hematopoiesis, Versiti Blood Research Institute, Milwaukee, WI, USA.ORCID 0009-0004-6779-1131
Anthony J VeltriProgram in Stem Cell Biology and Hematopoiesis, Versiti Blood Research Institute, Milwaukee, WI, USA.ORCID 0000-0002-7067-1796
Shikan ZhengProgram in Stem Cell Biology and Hematopoiesis, Versiti Blood Research Institute, Milwaukee, WI, USA.ORCID 0000-0002-8968-9742
Robert BurnsProgram in Stem Cell Biology and Hematopoiesis, Versiti Blood Research Institute, Milwaukee, WI, USA.
Nan ZhuProgram in Stem Cell Biology and Hematopoiesis, Versiti Blood Research Institute, Milwaukee, WI, USA.
Sridhar RaoProgram in Stem Cell Biology and Hematopoiesis, Versiti Blood Research Institute, Milwaukee, WI, USA.ORCID 0000-0003-2688-9541
Carsten Muller-TidowDepartment of Medicine, Hematology, Oncology, University Hospital Heidelberg, Heidelberg, Germany.
John H BushwellerDepartment of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, VA, USA.ORCID 0000-0002-5386-1758
John A PulikkanProgram in Stem Cell Biology and Hematopoiesis, Versiti Blood Research Institute, Milwaukee, WI, USA.ORCID 0000-0001-7995-6942
Versiti Blood Center of Wisconsin · USMedical College of Wisconsin · USHeidelberg University · DEUniversity of Virginia · US

Funding

Targeted Small Molecule Inhibitors for Inv(16) LeukemiaR01CA234478 · NCI · UNIVERSITY OF VIRGINIA · PI BUSHWELLER, JOHN HACKETT, CASTILLA, LUCIO H. · 2019 to 2023
$3.4M
NCI NIH HHS R01 CA234478
6 · The paper itself

Abstract

N-MYC (encoded by

Indexed as

Leukemia, Myeloid, AcuteCarcinogenesisCell SurvivalHematopoietic Stem CellsHumansN-Myc Proto-Oncogene ProteinN-Myc Proto-Oncogene Protein

Identifiers

PMID38416825
PMCPMC10901375
OpenAlexW4392266033

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.