Evidence map›Paper›PMID 38418668›Full record

ReviewHandbook of experimental pharmacology2025

Plant-Derived Natural Products for the Treatment of Bacterial Infections.

Francisco Javier Álvarez-Martínez, Rocío Díaz-Puertas, Enrique Barrajón-Catalán, Vicente Micol

Abstract readReview
PubMed Publisher
In one paragraph

Review in Handbook of experimental pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
11.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Antimicrobial effects of compound Huangbai liquid onAmerican journal of translational research · 2026
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Francisco Javier Álvarez-MartínezInstitute for Research, Development and Innovation in Health Biotechnology of Elche (IDiBE), Miguel Hernández University (UMH), Elche, Spain.
Rocío Díaz-PuertasInstitute for Research, Development and Innovation in Health Biotechnology of Elche (IDiBE), Miguel Hernández University (UMH), Elche, Spain.
Enrique Barrajón-CatalánInstitute for Research, Development and Innovation in Health Biotechnology of Elche (IDiBE), Miguel Hernández University (UMH), Elche, Spain. e.barrajon@umh.es.
Vicente MicolInstitute for Research, Development and Innovation in Health Biotechnology of Elche (IDiBE), Miguel Hernández University (UMH), Elche, Spain.
Hospital General Universitario de Alicante Doctor Balmis · ESSpanish Biomedical Research Centre in Physiopathology of Obesity and Nutrition · ESUniversitat de Miguel Hernández d'Elx · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial infections are a significant public health concern, and the emergence of antibiotic-resistant bacteria (ARB) has become a major challenge for modern medicine. The overuse and misuse of antibiotics have contributed to the development of ARB, which has led to the need for alternative therapies. Plant-derived natural products (PNPs) have been extensively studied for their potential as alternative therapies for the treatment of bacterial infections. The diverse chemical compounds found in plants have shown significant antibacterial properties, making them a promising source of novel antibacterial agents. The use of PNPs as antibacterial agents is particularly appealing because they offer a relatively safe and cost-effective approach to the treatment of bacterial infections. This chapter aims to provide an overview of the current state of research on PNPs as antibacterial agents. It will cover the mechanisms of action of the main PNPs against bacterial pathogens and discuss their potential to be used as complementary therapies to combat ARB. This chapter will also highlight the most common screening methodologies to discover new PNPs and the challenges and future prospects in the development of these compounds as antibacterial agents.

Indexed as

Anti-Bacterial AgentsBacterial InfectionsBiological ProductsAnimalsBacteriaHumansAnti-Bacterial AgentsBiological ProductsAntibacterialAntibiotic resistanceBacteriaMedicineNatural productPlant

Identifiers

PMID38418668
OpenAlexW4393107030

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.