Evidence map›Paper›PMID 38418874›Full record

ArticleNature2024

Incomplete transcripts dominate the Mycobacterium tuberculosis transcriptome.

Xiangwu Ju, Shuqi Li, Ruby Froom, Ling Wang, Mirjana Lilic, Madeleine Delbeau, Elizabeth A Campbell, Jeremy M Rock, Shixin Liu

Open access · hybridAbstract read
In one paragraph

Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 24 citations in OpenAlex.

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  7. Structural principles of transcriptional collisions.bioRxiv : the preprint server for biology · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Xiangwu JuLaboratory of Nanoscale Biophysics and Biochemistry, The Rockefeller University, New York, NY, USA.
Shuqi LiLaboratory of Host-Pathogen Biology, The Rockefeller University, New York, NY, USA.
Ruby FroomLaboratory of Host-Pathogen Biology, The Rockefeller University, New York, NY, USA.ORCID 0000-0002-5826-0708
Ling WangLaboratory of Nanoscale Biophysics and Biochemistry, The Rockefeller University, New York, NY, USA.
Mirjana LilicLaboratory of Molecular Biophysics, The Rockefeller University, New York, NY, USA.ORCID 0000-0002-2669-3998
Madeleine DelbeauLaboratory of Molecular Biophysics, The Rockefeller University, New York, NY, USA.
Elizabeth A CampbellLaboratory of Molecular Biophysics, The Rockefeller University, New York, NY, USA.ORCID 0000-0002-1332-128X
Jeremy M RockLaboratory of Host-Pathogen Biology, The Rockefeller University, New York, NY, USA. rock@rockefeller.edu.ORCID 0000-0002-9310-951X
Shixin LiuLaboratory of Nanoscale Biophysics and Biochemistry, The Rockefeller University, New York, NY, USA. shixinliu@rockefeller.edu.ORCID 0000-0003-4238-7066
Rockefeller University · US

Funding

Structure/function analyses of essential mycobacterial transcription regulatorsR01GM114450 · NIGMS · ROCKEFELLER UNIVERSITY · PI CAMPBELL, ELIZABETH A · 2015 to 2023
$3.4M
Towards a molecular understanding of persistent tuberculosis infectionDP2AI144850 · NIAID · ROCKEFELLER UNIVERSITY · PI ROCK, JEREMY MICHAEL · 2018 to 2018
$2.5M
Probing Symmetry Breaking in Epigenetic Inheritance: From Single Molecules to Systems BiologyDP2HG010510 · NHGRI · ROCKEFELLER UNIVERSITY · PI LIU, SHIXIN · 2018 to 2018
$2.5M
Genetics and Cell Biology Training ProgramT32GM144299 · NIGMS · ROCKEFELLER UNIVERSITY · PI Viviana I Risca, Tim Stearns · 2022 to 2026
$2.1M
NHGRI NIH HHS DP2 HG010510NIAID NIH HHS DP2 AI144850NIGMS NIH HHS R01 GM114450NIGMS NIH HHS T32 GM144299
6 · The paper itself

Abstract

Mycobacterium tuberculosis (Mtb) is a bacterial pathogen that causes tuberculosis (TB), an infectious disease that is responsible for major health and economic costs worldwide

Indexed as

Gene Expression Regulation, BacterialMycobacterium tuberculosisRNA, BacterialTranscriptomeDNA-Directed RNA PolymerasesProtein BiosynthesisRibosomesRNA, MessengerSigma FactorTranscription Initiation SiteTuberculosisDNA-Directed RNA PolymerasesRNA, BacterialRNA, MessengerSigma Factor

Identifiers

PMID38418874
PMCPMC10937400
OpenAlexW4392242606

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.