Evidence map›Paper›PMID 38419016›Full record

ArticleCardiovascular diabetology2024

Non-insulin-based insulin resistance indexes in predicting atrial fibrillation recurrence following ablation: a retrospective study.

Zhe Wang, Haoming He, Yingying Xie, Jiaju Li, Fangyuan Luo, Zhaowei Sun, Shuwen Zheng, Furong Yang, Xuexi Li, Xiaojie Chen and 2 more

Open access · goldAbstract read
In one paragraph

Article in Cardiovascular diabetology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 3 pooled it
16.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 3 syntheses or guidelines pooled it, 42 citations in OpenAlex.

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  8. Predictors of atrial fibrillation recurrence after catheter ablation: a systematic review.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Zhe Wang *Department of Cardiology, China-Japan Friendship Hospital (Institute of Clinical Medical Sciences), Chinese Academy of Medical Sciences & Peking Union Medical College, No.2 East Yinghua Road, Chaoyang District, Beijing, 100029, China.
Haoming He *Department of Cardiology, China-Japan Friendship Hospital (Institute of Clinical Medical Sciences), Chinese Academy of Medical Sciences & Peking Union Medical College, No.2 East Yinghua Road, Chaoyang District, Beijing, 100029, China.
Yingying Xie *Department of Cardiology, China-Japan Friendship Hospital (Institute of Clinical Medical Sciences), Chinese Academy of Medical Sciences & Peking Union Medical College, No.2 East Yinghua Road, Chaoyang District, Beijing, 100029, China.
Jiaju LiDepartment of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Fangyuan LuoDepartment of Cardiology, China-Japan Friendship Hospital (Institute of Clinical Medical Sciences), Chinese Academy of Medical Sciences & Peking Union Medical College, No.2 East Yinghua Road, Chaoyang District, Beijing, 100029, China.
Zhaowei SunDepartment of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Shuwen ZhengDepartment of Cardiology, Beijing University of Chinese Medicine China-Japan Friendship School of Clinical Medicine, Beijing, China.
Furong YangDepartment of Cardiology, Beijing University of Chinese Medicine China-Japan Friendship School of Clinical Medicine, Beijing, China.
Xuexi LiDepartment of Cardiology, China-Japan Friendship Hospital (Institute of Clinical Medical Sciences), Chinese Academy of Medical Sciences & Peking Union Medical College, No.2 East Yinghua Road, Chaoyang District, Beijing, 100029, China.
Xiaojie ChenDepartment of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Yingwei ChenDepartment of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Yihong SunDepartment of Cardiology, China-Japan Friendship Hospital (Institute of Clinical Medical Sciences), Chinese Academy of Medical Sciences & Peking Union Medical College, No.2 East Yinghua Road, Chaoyang District, Beijing, 100029, China. yihongsun72@163.com.
China-Japan Friendship Hospital · CNFirst Affiliated Hospital of Zhengzhou University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNBeijing University of Chinese Medicine · CN

Funding

Beijing Medical and Health Fund 2022-HX-23Capital Health Research and Development of Special Fund 2022-2-4065National High Level Hospital Clinical Research Fund National High Level Hospital Clinical Research Fund
6 · The paper itself

Abstract

backgroundInsulin resistance (IR) is involved in the pathophysiological processes of arrhythmias. Increasing evidence suggests triglyceride and glucose (TyG) index, metabolic score for insulin resistance (METS-IR), triglyceride glucose-body mass index (TyG-BMI), and triglyceride to high-density lipoprotein cholesterol (TG/HDL-C) ratio are simple and reliable surrogates for IR. Although they have been associated with atrial fibrillation (AF), evidence supporting this is limited. Here, this is the first study to investigate the association between TyG-BMI index and AF recurrence following radiofrequency catheter ablation (RFCA). The performance of the four non-insulin-based IR indexes in predicting AF recurrence after ablation was explored.

methodsA total of 2242 AF patients who underwent a de novo RFCA between June 2018 to January 2022 at two hospitals in China were included in this retrospective study. The predictive values of IR indexes for AF recurrence after ablation were assessed.

resultsDuring 1-year follow-up, 31.7% of patients experienced AF recurrence. The multivariable analysis revealed that TyG index, METS-IR, and TyG-BMI index were independent risk factors for AF recurrence. Restricted cubic spline analysis revealed a connection between METS-IR, TyG-BMI index, and AF recurrence (P < 0.001). Furthermore, incorporating the METS-IR or TyG-BMI index to the basic risk model with fully adjusted factors considerably enhanced the forecast of AF recurrence, as demonstrated by the C-statistic, continuous net reclassification improvement, and integrated discrimination improvement.

conclusionsTyG index, METS-IR, and TyG-BMI index were independently associated with AF recurrence following ablation. Among the four non-insulin-based IR indexes, TyG-BMI had the highest predictive value, followed by METS-IR.

Indexed as

Atrial FibrillationInsulin ResistanceBiomarkersBlood GlucoseGlucoseHumansRetrospective StudiesTriglyceridesBiomarkersBlood GlucoseGlucoseTriglyceridesAtrial fibrillationMetabolic score for insulin resistanceRadiofrequency ablationRecurrenceTriglyceride glucose-body mass index

Identifiers

PMID38419016
PMCPMC10902970
OpenAlexW4392242918

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.