Evidence map›Paper›PMID 38419877›Full record

ArticleNanoscale advances2024

Pen direct writing of SERRS-based lateral flow assays for detection of penicillin G in milk.

Alida Russo, Simone Cavalera, Richard Murray, Pierre Lovera, Aidan Quinn, Laura Anfossi, Daniela Iacopino

Abstract read
In one paragraph

Article in Nanoscale advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alida RussoTyndall National Institute, University College Cork Lee Maltings Complex, Dyke Parade T12R5CP Cork Ireland daniela.iacopino@tyndall.ie.ORCID https://orcid.org/0000-0003-3806-4010
Simone CavaleraDepartment of Chemistry, University of Turin Via P. Giuria 5 10125 Turin Italy.ORCID https://orcid.org/0000-0002-5353-647X
Richard MurrayTyndall National Institute, University College Cork Lee Maltings Complex, Dyke Parade T12R5CP Cork Ireland daniela.iacopino@tyndall.ie.ORCID https://orcid.org/0000-0003-0676-5111
Pierre LoveraTyndall National Institute, University College Cork Lee Maltings Complex, Dyke Parade T12R5CP Cork Ireland daniela.iacopino@tyndall.ie.
Aidan QuinnTyndall National Institute, University College Cork Lee Maltings Complex, Dyke Parade T12R5CP Cork Ireland daniela.iacopino@tyndall.ie.ORCID https://orcid.org/0000-0003-4021-9990
Laura AnfossiDepartment of Chemistry, University of Turin Via P. Giuria 5 10125 Turin Italy.ORCID https://orcid.org/0000-0002-2920-0140
Daniela IacopinoTyndall National Institute, University College Cork Lee Maltings Complex, Dyke Parade T12R5CP Cork Ireland daniela.iacopino@tyndall.ie.ORCID https://orcid.org/0000-0003-2301-9401

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Direct pen writing offers versatile opportunities for development of low-cost tests for point-of-care applications. In this work a lateral flow immunoassay (LFIA) test was fabricated by hand "writing" immunoprobes onto hand-cut nitrocellulose strips with a commercial fountain pen. The qualitative capabilities of the test were extended by addition of a Raman reporter and consequent design and fabrication of a Surface Enhanced Resonant Raman Scattering (SERRS)-LFIA test. As proof-of-concept, dual detection of penicillin G was achieved in milk with a visual LOD of 20 ppm and a dynamic range of 0.03-97.5 ppm. Evaluation against equivalent tests performed with conventionally prepared LFIA strips showed comparable results, thus demonstrating the validity of the test. These results demonstrate the potential for further decrease in cost and consequent broader use of LFIA tests in remote regions and resource-limited environments.

Identifiers

PMID38419877
PMCPMC10898433

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.