Evidence map›Paper›PMID 38424273›Full record

ArticleNature cell biology2024

Evidence for widespread cytoplasmic structuring into mesoscale condensates.

Felix C Keber, Thao Nguyen, Andrea Mariossi, Clifford P Brangwynne, Martin Wühr

Abstract read
In one paragraph

Article in Nature cell biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed.

  1. Review
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  3. Article
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  6. Article
  7. Subcellular localization as a driver of protein function.Nature reviews. Molecular cell biology · 2026
    Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Oligomerization of PER2 as a dynamic mode of regulation of the mammalian circadian clock.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  13. Article
  14. Article
  15. Control of encounter kinetics by chemically active droplets.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Felix C KeberDepartment of Molecular Biology, Princeton University, Princeton, NJ, USA.ORCID http://orcid.org/0000-0003-0384-2919
Thao NguyenDepartment of Chemical and Biological Engineering, Princeton University, Princeton, NJ, USA.
Andrea MariossiDepartment of Molecular Biology, Princeton University, Princeton, NJ, USA.
Clifford P BrangwynneDepartment of Chemical and Biological Engineering, Princeton University, Princeton, NJ, USA. cbrangwy@princeton.edu.ORCID http://orcid.org/0000-0002-1350-9960
Martin WührDepartment of Molecular Biology, Princeton University, Princeton, NJ, USA. wuhr@princeton.edu.ORCID http://orcid.org/0000-0002-0244-8947

Funding

Development of New Proteomics Technology and its Application to Study Cellular OrganizationR35GM128813 · NIGMS · PRINCETON UNIVERSITY · PI Martin Wühr · 2018 to 2026
$4.0M
Howard Hughes Medical InstituteNIGMS NIH HHS R35 GM128813
6 · The paper itself

Abstract

Compartmentalization is an essential feature of eukaryotic life and is achieved both via membrane-bound organelles, such as mitochondria, and membrane-less biomolecular condensates, such as the nucleolus. Known biomolecular condensates typically exhibit liquid-like properties and are visualized by microscopy on the scale of ~1 µm (refs.

Indexed as

Cell NucleolusMicroscopyCytoplasmMitochondriaProteomeProteome

Identifiers

PMID38424273
PMCPMC10981939

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.