Evidence map›Paper›PMID 38430311›Full record

ReviewCurrent pain and headache reports2024

Benefit of Dietary Supplementation of Nutraceuticals as an Integrative Approach for Management of Migraine: Evidence From Preclinical and Clinical Studies.

Paul L Durham, Sophia R Antonopoulos

Open access · greenAbstract readReview
In one paragraph

Review in Current pain and headache reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
  2. Nutraceuticals: a promising, yet unregulated Frontier in Healthcare.European journal of clinical nutrition · 2025
    Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Paul L DurhamDepartment of Biology, Missouri State University, Jordan Valley Innovation Center, 524 North Boonville Ave, Springfield, MO, 65806, USA. pauldurham@missouristate.edu.
Sophia R AntonopoulosDepartment of Biology, Missouri State University, Jordan Valley Innovation Center, 524 North Boonville Ave, Springfield, MO, 65806, USA.
Missouri State University · US

Funding

Grape Seed Extract Modulation of Peripheral and Central Nervous System Neuron-Glia InteractionsR15AT012501 · NCCIH · MISSOURI STATE UNIVERSITY · PI DURHAM, PAUL L · 2024 to 2024
$428k
NCCIH NIH HHS R15 AT012501
6 · The paper itself

Abstract

purpose of reviewTo provide information from preclinical and clinical studies on the biological activity and health benefits of dietary inclusion of nutraceuticals as a safe, effective, non-pharmacological approach for the treatment of migraine. RECENT

findingsThere is emerging evidence of the therapeutic benefit of nutraceuticals to inhibit oxidative stress, suppress inflammation, and prevent changes in the normal gut microbiome, which are implicated in migraine pathology. Nutraceuticals can be enriched in polyphenols, which act as molecular scavengers to reduce the harmful effects of reactive oxygen species and phytosterols that suppress inflammation. Nutraceuticals also function to inhibit dysbiosis and to maintain the commensal intestinal bacteria that produce anti-inflammatory molecules including short-chain fatty acids that can act systemically to maintain a healthy nervous system. Dietary inclusion of nutraceuticals that exhibit antioxidant, anti-inflammatory, and anti-nociceptive properties and maintain the gut microbiota provides a complementary and integrative therapeutic strategy for migraine.

Indexed as

Dietary SupplementsGastrointestinal MicrobiomeMigraine DisordersAnimalsAntioxidantsHumansOxidative StressAntioxidantsAnti-inflammatoryAntioxidantGut microbiomeMigraineMineralNutraceutical

Identifiers

PMID38430311
PMCPMC12019864
OpenAlexW4392348582

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.