Evidence map›Paper›PMID 38431557›Full record

Observational studyBMC pulmonary medicine2024

Clinical trends among patients with asthma hospitalized for COVID-19 based on data from a nationwide database: an observational study.

Akinari Tsukada, Junko Terada-Hirashima, Jin Takasaki, Hiroshi Nokihara, Shinyu Izumi, Masayuki Hojo, Haruhito Sugiyama

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in BMC pulmonary medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Akinari TsukadaDepartment of Respiratory Medicine, National Center for Global Health and Medicine, Tokyo, 162-8655, Japan. atsukada@hosp.ncgm.go.jp.
Junko Terada-HirashimaDepartment of Respiratory Medicine, National Center for Global Health and Medicine, Tokyo, 162-8655, Japan.
Jin TakasakiDepartment of Respiratory Medicine, National Center for Global Health and Medicine, Tokyo, 162-8655, Japan.
Hiroshi NokiharaDepartment of Respiratory Medicine, National Center for Global Health and Medicine, Tokyo, 162-8655, Japan.
Shinyu IzumiDepartment of Respiratory Medicine, National Center for Global Health and Medicine, Tokyo, 162-8655, Japan.
Masayuki HojoDepartment of Respiratory Medicine, National Center for Global Health and Medicine, Tokyo, 162-8655, Japan.
Haruhito SugiyamaDepartment of Respiratory Medicine, National Center for Global Health and Medicine, Tokyo, 162-8655, Japan.
National Center for Global Health and Medicine · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhile the prevalence of severe cases and mortality rate of coronavirus disease 2019 (COVID-19) appear to be reducing, the clinical characteristics and severity of hospitalized patients with asthma and COVID-19 remain largely unknown. This study aimed to examine the association of asthma with COVID-19 severity and mortality risk.

methodsData from the Japanese COVID-19 Registry Database were used to investigate the association between COVID-19 and asthma. This study focused on patients hospitalized for COVID-19 in 690 facilities from January 31, 2020, to December 31, 2022. Multivariate analysis using logistic regression was conducted to assess whether asthma, compared with other conditions, represents a risk factor for mortality and invasive mechanical ventilation after COVID-19.

resultsIn total, 72,582 patients with COVID-19 were included in the analysis, of whom, 3731 were diagnosed with asthma. From January 2020 to June 2021, asthma showed no significant association with an increase in mortality (OR 0.837, 95% CI 0.639-1.080, p = 0.184) or invasive mechanical ventilation events (OR 1.084, 95% CI 0.878-1.326, p = 0.440). An analysis conducted after July 2021 yielded similar results. For patients with asthma, factors such as age, body-mass index, sex, and chronic kidney disease increased the risk of mechanical ventilation. However, non-vaccination status and high blood pressure increased the risk of mechanical ventilation during the second half of the study.

conclusionPatients with asthma did not have an increased risk of mortality or mechanical ventilation due to COVID-19. However, patients with asthma had a higher risk of more severe COVID-19 due to factors such as advancing age, elevated body-mass index, chronic kidney disease, and non-vaccination.

Indexed as

AsthmaCOVID-19Renal Insufficiency, ChronicHumansRespiration, ArtificialRisk FactorsAsthmaCOPDCOVID-19IntubationMortalityVaccination

Identifiers

PMID38431557
PMCPMC10909272
OpenAlexW4392348048

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.