Evidence map›Paper›PMID 38431850›Full record

ArticleEmerging microbes & infections2024

Lansoprazole interferes with fungal respiration and acts synergistically with amphotericin B against multidrug-resistant

Ehab A Salama, Yehia Elgammal, Aruna Wijeratne, Nadia A Lanman, Sagar M Utturkar, Atena Farhangian, Jianing Li, Brigitte Meunier, Tony R Hazbun, Mohamed N Seleem

Open access · goldAbstract read
In one paragraph

Article in Emerging microbes & infections, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. bioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Overcoming amphotericin B resistance inAntimicrobial agents and chemotherapy · 2024
    Article
  12. Current issues in molecular biology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Ehab A SalamaDepartment of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, USA.
Yehia ElgammalDepartment of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, USA.
Aruna WijeratneDepartment of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Nadia A LanmanPurdue Institute for Cancer Research, Purdue University, West Lafayette, Indiana, USA.
Sagar M UtturkarPurdue Institute for Cancer Research, Purdue University, West Lafayette, Indiana, USA.
Atena FarhangianDepartment of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN, USA.
Jianing LiDepartment of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN, USA.
Brigitte MeunierInstitute for Integrative Biology of the Cell (I2BC), Université Paris-Saclay, CEA, CNRS, Gif-sur-Yvette, France.
Tony R HazbunPurdue Institute for Cancer Research, Purdue University, West Lafayette, Indiana, USA.
Mohamed N SeleemDepartment of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, USA.
Purdue University West Lafayette · USVirginia Tech · USCentre National de la Recherche Scientifique · FRIndiana University – Purdue University Indianapolis · USVirginia–Maryland College of Veterinary Medicine · US

Funding

Transgenic Mouse Core Facility Shared Resource (TMCF-SR)P30CA023168 · NCI · PURDUE UNIVERSITY WEST LAFAYETTE · PI Andrea L Kasinski · 1985 to 2026
$43.4M
Rapid AST through Metabolic Imaging at Single Cell LevelR01AI141439 · NIAID · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI Ji-Xin Cheng · 2019 to 2026
$4.7M
Structure, Mechanism, and Regulation of PACAP/VIP GPCR SubtypesR01GM129431 · NIGMS · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI LI, JIANING · 2018 to 2022
$1.7M
Precision Design of Antimicrobial Peptides Against Bacterial InfectionsR01GM143370 · NIGMS · PURDUE UNIVERSITY · PI LI, JIANING · 2022 to 2025
$1.2M
NCI NIH HHS P30 CA023168NIAID NIH HHS R01 AI141439NIGMS NIH HHS R01 GM129431NIGMS NIH HHS R01 GM143370
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Amphotericin BAntifungal AgentsCandidiasisAnimalsCandida aurisCytochromesLansoprazoleMiceRespirationAmphotericin BAntifungal AgentsCytochromesLansoprazoleC. auriscytochrome bc1fungal respirationIn vivo mouse modelLansoprazolemetabolitesPISA analysis

Identifiers

PMID38431850
PMCPMC10911247
OpenAlexW4392344298

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.