Evidence map›Paper›PMID 38433145›Full record

ArticleArchives of microbiology2024

Self-assembled micelles loaded with itraconazole as anti-Acanthamoeba nano-formulation.

Komal Rao, Muhammad Abdullah, Usman Ahmed, Hashi Isse Wehelie, Muhammad Raza Shah, Ruqaiyyah Siddiqui, Naveed A Khan, Bader S Alawfi, Ayaz Anwar

Abstract read
PubMed Publisher
In one paragraph

Article in Archives of microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.9field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 5 countries.

Komal RaoInternational Center for Chemical and Biological Sciences, HEJ Research Institute of Chemistry, Karachi University, Karachi, 75270, Pakistan.
Muhammad AbdullahInternational Center for Chemical and Biological Sciences, HEJ Research Institute of Chemistry, Karachi University, Karachi, 75270, Pakistan.
Usman AhmedDepartment of Biological Sciences, School of Medical and Life Sciences, Sunway University, 47500, Subang Jaya, Selangor, Malaysia.
Hashi Isse WehelieDepartment of Biological Sciences, School of Medical and Life Sciences, Sunway University, 47500, Subang Jaya, Selangor, Malaysia.
Muhammad Raza ShahInternational Center for Chemical and Biological Sciences, HEJ Research Institute of Chemistry, Karachi University, Karachi, 75270, Pakistan.
Ruqaiyyah SiddiquiInstitute of Biological Chemistry, Biophysics and Bioengineering, Heriot-Watt University Edinburgh, Edinburgh, EH14 4AS, UK.
Naveed A KhanMicrobiota Research Center, Istinye University, 34010, Istanbul, Turkey. naveed5438@gmail.com.
Bader S AlawfiDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Taibah University, 42353, Madinah, Saudi Arabia.
Ayaz AnwarDepartment of Biological Sciences, School of Medical and Life Sciences, Sunway University, 47500, Subang Jaya, Selangor, Malaysia. ayazanwarkk@yahoo.com.
International Center for Chemical and Biological Sciences · PKSunway University · MYHeriot-Watt University · GBIstinye University · TRTaibah University · SA

Funding

Sunway University GRTIN-RRO-46-2022
6 · The paper itself

Abstract

Acanthamoeba castellanii are opportunistic pathogens known to cause infection of the central nervous system termed: granulomatous amoebic encephalitis, that mostly effects immunocompromised individuals, and a sight threatening keratitis, known as Acanthamoeba keratitis, which mostly affects contact lens wearers. The current treatment available is problematic, and is toxic. Herein, an amphiphilic star polymer with AB

Indexed as

Acanthamoeba castellaniiMicellesAlkynesHumansItraconazolePolymersAlkynesItraconazoleMicellesPolymersAcanthamoebaCentral nervous systemFree-living amoebaeInfectious diseasesItraconazoleMicellesNanoformulationNanotechnology

Identifiers

PMID38433145
OpenAlexW4392402082

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.