Evidence map›Paper›PMID 38433862›Full record

ArticleFrontiers in cellular neuroscience2024

Protein kinase Cγ negatively regulates the intrinsic excitability in zebrin-negative cerebellar Purkinje cells.

Masashi Watanave, Mika Kawachi, Ayumu Konno, Ryo Aoki, Yuuki Fukai, Yasunori Matsuzaki, Ryosuke Kaneko, Hirokazu Hirai

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Masashi WatanaveDepartment of Neurophysiology and Neural Repair, Gunma University Graduate School of Medicine, Maebashi, Japan.
Mika KawachiDepartment of Neurophysiology and Neural Repair, Gunma University Graduate School of Medicine, Maebashi, Japan.
Ayumu KonnoDepartment of Neurophysiology and Neural Repair, Gunma University Graduate School of Medicine, Maebashi, Japan.
Ryo AokiDepartment of Neurophysiology and Neural Repair, Gunma University Graduate School of Medicine, Maebashi, Japan.
Yuuki FukaiDepartment of Neurophysiology and Neural Repair, Gunma University Graduate School of Medicine, Maebashi, Japan.
Yasunori MatsuzakiDepartment of Neurophysiology and Neural Repair, Gunma University Graduate School of Medicine, Maebashi, Japan.
Ryosuke KanekoKOKORO-Biology Group, Neuroscience Laboratories, Graduate School of Frontier Biosciences, Osaka University, Osaka, Japan.
Hirokazu HiraiDepartment of Neurophysiology and Neural Repair, Gunma University Graduate School of Medicine, Maebashi, Japan.
Gunma University · JPThe University of Osaka · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Protein kinase C γ (PKCγ), a neuronal isoform present exclusively in the central nervous system, is most abundantly expressed in cerebellar Purkinje cells (PCs). Targeted deletion of PKCγ causes a climbing fiber synapse elimination in developing PCs and motor deficit. However, physiological roles of PKCγ in adult mouse PCs are little understood. In this study, we aimed to unravel the roles of PKCγ in mature mouse PCs by deleting PKCγ from adult mouse PCs of PKCγ

Indexed as

action potentialaldolase Ccerebellumheterogeneityprotein kinasePurkinje cellszebrin

Identifiers

PMID38433862
PMCPMC10904455
OpenAlexW4391880383

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.