Evidence map›Paper›PMID 38437537›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Sustained AhR activity programs memory fate of early effector CD8

Huafeng Zhang, Zhuoshun Yang, Wu Yuan, Jincheng Liu, Xiao Luo, Qian Zhang, Yonggang Li, Jie Chen, Yabo Zhou, Jiadi Lv and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. IL-15/NKG2D signaling-mediated activation of CD8Journal of thoracic disease · 2026
    Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Metabolic Checkpoints in CD8International journal of biological sciences · 2026
    Review
  9. Article
  10. EnhancedScience advances · 2025
    Article
  11. Review
  12. Article
  13. The role of the AHR in host-pathogen interactions.Nature reviews. Immunology · 2025
    Review
  14. Review
  15. Article
  16. Review
  17. Article
  18. Targeting ROS in cancer: rationale and strategies.Nature reviews. Drug discovery · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 1 country.

Huafeng Zhang *Department of Pathology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Zhuoshun Yang *Institute of Biomedical Research, Department of Infectious Diseases, Regulatory Mechanism and Targeted Therapy for Liver Cancer Shiyan Key Laboratory, Hubei Provincial Clinical Research Center for Precise Diagnosis and Treatment of Liver Cancer, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei 442000, China.
Wu Yuan *Department of Biochemistry and Molecular Biology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Jincheng Liu *Department of Biochemistry and Molecular Biology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Xiao LuoDepartment of Pathology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Qian ZhangDepartment of Pathology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Yonggang LiHubei Provincial Key Laboratory for Applied Toxicology, Hubei Provincial Center for Disease Control and Prevention, Wuhan 430079, China.
Jie ChenDepartment of Immunology and National Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100005, China.
Yabo ZhouDepartment of Immunology and National Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100005, China.ORCID 0000-0002-0519-2158
Jiadi LvDepartment of Immunology and National Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100005, China.
Nannan ZhouDepartment of Immunology and National Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100005, China.
Jingwei MaDepartment of Immunology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Ke TangDepartment of Biochemistry and Molecular Biology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Bo HuangDepartment of Biochemistry and Molecular Biology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.ORCID 0000-0001-8476-1138
Huazhong University of Science and Technology · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNHubei Provincial Center for Disease Control and Prevention · CNHubei University of Medicine · CNTongji Hospital · CN

Funding

CAMS | Chinese Academy of Medical Sciences Initiative for Innovative Medicine () 2021-I2M-1-021Haihe Laboratory of Cell Ecosystem Innovation Fund 22HHXBSS00009MOST | National Natural Science Foundation of China (NSFC) 32322030MOST | National Natural Science Foundation of China (NSFC) 82271759MOST | National Natural Science Foundation of China (NSFC) 82388201
6 · The paper itself

Abstract

Identification of mechanisms that program early effector T cells to either terminal effector T (T

Indexed as

CD8-Positive T-LymphocytesCell DivisionCytosolReactive Oxygen SpeciesReactive Oxygen Speciesaryl hydrocarbon receptorCD8+ memory T cellsHIF-1αtranscription factor

Identifiers

PMID38437537
PMCPMC10945852
OpenAlexW4392382893

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.