ReviewFood and energy security2023
WHIRLY protein functions in plants.
Review in Food and energy security, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 26 citations in OpenAlex.
- A WHY1-NADK3-PEX5 module confers drought tolerance by maintaining peroxisomal ROS homeostasis in Brassica napus.The Plant journal : for cell and molecular biology · 2026Article
- Turning over a green leaf: integrating light signals toward chloroplast establishment.Plant physiology · 2026Review
- Arbuscular mycorrhizal fungi as integrative modulators of plant tolerance to drought, salinity, and heavy metal stress: mechanistic insights and future directions.Journal, genetic engineering & biotechnology · 2026Review
- Chloroplast Responses to Drought: Integrative Mechanisms and Mitigation Strategies.International journal of molecular sciences · 2025Review
- The "WHY" behind pear pollen tube growth.Plant physiology · 2025Article
- Functional Characterization of thePlants (Basel, Switzerland) · 2025Article
- WHIRLY1 regulates aliphatic glucosinolate biosynthesis in early seedling development of Arabidopsis.The Plant journal : for cell and molecular biology · 2025Article
- Genome-Wide Identification and Expression Analysis of the Sweet Cherry Whirly Gene Family.Current issues in molecular biology · 2024Article
- Article
- A molecular atlas of plastid and mitochondrial proteins reveals organellar remodeling during plant evolutionary transitions from algae to angiosperms.PLoS biology · 2024Article
- Evolution ofFrontiers in plant science · 2024Article
- How do barley plants with impaired photosynthetic light acclimation survive under high-light stress?Planta · 2023Article
- WHIRLY proteins maintain seed longevity by effects on seed oxygen signalling during imbibition.The Biochemical journal · 2023Article
- WHIRLY1 Acts Upstream of ABA-Related Reprogramming of Drought-Induced Gene Expression in Barley and Affects Stress-Related Histone Modifications.International journal of molecular sciences · 2023Article
- WHIRLY protein functions in plants.Food and energy security · 2023Review
- The potentiality of biostimulant (Lawsonia inermis L.) on some morpho-physiological, biochemical traits, productivity and grain quality of Triticum aestivum L.BMC plant biology · 2023Article
- Identification of Whirly transcription factors in Triticeae species and functional analysis ofFrontiers in plant science · 2023Article
- Genome-wide identification, phylogenetic, and expression analysis under abiotic stress conditions of Whirly (WHY) gene family in Medicago sativa L.Scientific reports · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Environmental stresses pose a significant threat to food security. Understanding the function of proteins that regulate plant responses to biotic and abiotic stresses is therefore pivotal in developing strategies for crop improvement. The WHIRLY (WHY) family of DNA-binding proteins are important in this regard because they fulfil a portfolio of important functions in organelles and nuclei. The WHY1 and WHY2 proteins function as transcription factors in the nucleus regulating phytohormone synthesis and associated growth and stress responses, as well as fulfilling crucial roles in DNA and RNA metabolism in plastids and mitochondria. WHY1, WHY2 (and WHY3 proteins in Arabidopsis) maintain organelle genome stability and serve as auxiliary factors for homologous recombination and double-strand break repair. Our understanding of WHY protein functions has greatly increased in recent years, as has our knowledge of the flexibility of their localization and overlap of functions but there is no review of the topic in the literature. Our aim in this review was therefore to provide a comprehensive overview of the topic, discussing WHY protein functions in nuclei and organelles and highlighting roles in plant development and stress responses. In particular, we consider areas of uncertainty such as the flexible localization of WHY proteins in terms of retrograde signalling connecting mitochondria, plastids, and the nucleus. Moreover, we identify WHY proteins as important targets in plant breeding programmes designed to increase stress tolerance and the sustainability of crop yield in a changing climate.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.