Evidence map›Paper›PMID 38443186›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2024

Ndnf Interneuron Excitability Is Spared in a Mouse Model of Dravet Syndrome.

Sophie R Liebergall, Ethan M Goldberg

Open access · greenAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Sophie R LiebergallDepartment of Neuroscience, The University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania 19104.
Ethan M GoldbergDepartment of Neuroscience, The University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania 19104 goldberge@chop.edu.ORCID 0000-0002-7404-735X
University of Pennsylvania · US

Funding

The Intellectual and Developmental Disabilities Research Center (IDDRC) at CHOP/PennP50HD105354 · NICHD · CHILDREN'S HOSP OF PHILADELPHIA · PI Michael Byrne Robinson · 2021 to 2026
$9.2M
Interneuron axonopathy underlies circuit dysfunction in a mouse model of Dravet syndromeR01NS110869 · NINDS · CHILDREN'S HOSP OF PHILADELPHIA · PI ETHAN M GOLDBERG · 2019 to 2026
$3.5M
Pathomechanisms of SCN3A-related neurodevelopmental disorderR01NS119977 · NINDS · CHILDREN'S HOSP OF PHILADELPHIA · PI GOLDBERG, ETHAN M · 2021 to 2025
$2.7M
Cellular and circuit function of Ndnf-expressing interneurons in a mouse model of a neurodevelopmental disorderF31NS132519 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI LIEBERGALL, SOPHIE ROSE · 2023 to 2025
$124k
NICHD NIH HHS P50 HD105354NINDS NIH HHS F31 NS132519NINDS NIH HHS R01 NS110869NINDS NIH HHS R01 NS119977
6 · The paper itself

Abstract

Dravet syndrome (DS) is a neurodevelopmental disorder characterized by epilepsy, developmental delay/intellectual disability, and features of autism spectrum disorder, caused by heterozygous loss-of-function variants in

Indexed as

Disease Models, AnimalEpilepsies, MyoclonicInterneuronsNAV1.1 Voltage-Gated Sodium ChannelAction PotentialsAnimalsFemaleMaleMiceMice, Inbred C57BLMice, TransgenicNAV1.1 Voltage-Gated Sodium ChannelScn1a protein, mouseDravet syndromeinterneuronsNav1.1NdnfneurogliaformSCN1A

Identifiers

PMID38443186
PMCPMC11044195
OpenAlexW4392451328

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.