Evidence map›Paper›PMID 38444909›Full record

ArticleBrain communications2024

Longitudinal default mode sub-networks in the language and visual variants of Alzheimer's disease.

Irene Sintini, Nick Corriveau-Lecavalier, David T Jones, Mary M Machulda, Jeffrey L Gunter, Christopher G Schwarz, Hugo Botha, Arenn F Carlos, Michael G Kamykowski, Neha Atulkumar Singh and 6 more

Open access · goldAbstract read
In one paragraph

Article in Brain communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 1 country.

Irene SintiniDepartment of Radiology, Mayo Clinic, Rochester, MN 55905, USA.
Nick Corriveau-LecavalierDepartment of Neurology, Mayo Clinic, Rochester, MN 55905, USA.ORCID https://orcid.org/0000-0002-6561-9870
David T JonesDepartment of Radiology, Mayo Clinic, Rochester, MN 55905, USA.ORCID https://orcid.org/0000-0002-4807-9833
Mary M MachuldaDepartment of Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55905, USA.
Jeffrey L GunterDepartment of Radiology, Mayo Clinic, Rochester, MN 55905, USA.
Christopher G SchwarzDepartment of Radiology, Mayo Clinic, Rochester, MN 55905, USA.ORCID https://orcid.org/0000-0002-1466-8357
Hugo BothaDepartment of Neurology, Mayo Clinic, Rochester, MN 55905, USA.ORCID https://orcid.org/0000-0003-4390-685X
Arenn F CarlosDepartment of Neurology, Mayo Clinic, Rochester, MN 55905, USA.ORCID https://orcid.org/0000-0002-2100-5033
Michael G KamykowskiDepartment of Information Technology, Mayo Clinic, Rochester, MN 55905, USA.
Neha Atulkumar SinghDepartment of Neurology, Mayo Clinic, Rochester, MN 55905, USA.ORCID https://orcid.org/0000-0002-3614-9179
Ronald C PetersenDepartment of Neurology, Mayo Clinic, Rochester, MN 55905, USA.
Clifford R JackDepartment of Radiology, Mayo Clinic, Rochester, MN 55905, USA.ORCID https://orcid.org/0000-0001-7916-622X
Val J LoweDepartment of Radiology, Mayo Clinic, Rochester, MN 55905, USA.
Jonathan Graff-RadfordDepartment of Neurology, Mayo Clinic, Rochester, MN 55905, USA.ORCID https://orcid.org/0000-0003-2770-0691
Keith A JosephsDepartment of Neurology, Mayo Clinic, Rochester, MN 55905, USA.ORCID https://orcid.org/0000-0003-2930-8634
Jennifer L WhitwellDepartment of Radiology, Mayo Clinic, Rochester, MN 55905, USA.ORCID https://orcid.org/0000-0001-6914-1563
Mayo Clinic · USMayo Clinic in Arizona · US

Funding

Research Education ComponentP30AG062677 · NIA · MAYO CLINIC ROCHESTER · PI KEJAL KANTARCI · 2019 to 2026
$33.5M
Molecular and structural imaging in atypical Alzheimer's disease: a longitudinal studyR01AG050603 · NIA · MAYO CLINIC ROCHESTER · PI WHITWELL, JENNIFER LOUISE · 2016 to 2025
$5.9M
NIA NIH HHS P30 AG062677NIA NIH HHS R01 AG050603
6 · The paper itself

Abstract

Disruption of the default mode network is a hallmark of Alzheimer's disease, which has not been extensively examined in atypical phenotypes. We investigated cross-sectional and 1-year longitudinal changes in default mode network sub-systems in the visual and language variants of Alzheimer's disease, in relation to age and tau. Sixty-one amyloid-positive Alzheimer's disease participants diagnosed with posterior cortical atrophy (

Indexed as

atypical Alzheimer’s diseasedefault mode networkfunctional MRInetwork failure quotienttau

Identifiers

PMID38444909
PMCPMC10914456
OpenAlexW4390659652

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.