Evidence map›Paper›PMID 38446905›Full record

ArticleInternational braz j urol : official journal of the Brazilian Society of Urology

Long-term functional outcomes and surgical retreatment after thulium laser enucleation of the prostate: A 10-year follow-up study.

Celeste Manfredi, Luigi Napolitano, Francesco Ditonno, Giovanni Maria Fusco, Carmelo Quattrone, Marco De Sio, Luca Romis, Filippo Riccardo, Maria Rosaria Nugnes, Giovanni Di Lauro and 1 more

Open access · diamondAbstract read
In one paragraph

Article in International braz j urol : official journal of the Brazilian Society of Urology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. [Impact of thulium laser enucleation of the prostateBeijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. MRI and biopsy in prostate cancer are the hot topic in this number of International Brazilian Journal of Urology.International braz j urol : official journal of the Brazilian Society of Urology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Celeste ManfrediDepartment of Woman - Unit of Urology, Child and General and Specialized Surgery, University of Campania "Luigi Vanvitelli", Naples, Italy.
Luigi NapolitanoDepartment of Neurosciences, Reproductive Sciences and Odontostomatology, Urology Unit, University of Naples "Federico II", Naples, Italy.
Francesco DitonnoDepartment of Urology, University of Verona, Azienda Ospedaliera Universitaria Integrata, Verona, Italy.
Giovanni Maria FuscoDepartment of Neurosciences, Reproductive Sciences and Odontostomatology, Urology Unit, University of Naples "Federico II", Naples, Italy.
Carmelo QuattroneDepartment of Woman - Unit of Urology, Child and General and Specialized Surgery, University of Campania "Luigi Vanvitelli", Naples, Italy.
Marco De SioDepartment of Woman - Unit of Urology, Child and General and Specialized Surgery, University of Campania "Luigi Vanvitelli", Naples, Italy.
Luca RomisUrology Complex Unit-ASL Napoli 2 Nord "Santa Maria delle Grazie" Hospital, Pozzuoli, Italy.
Filippo RiccardoUrology Complex Unit-ASL Napoli 2 Nord "Santa Maria delle Grazie" Hospital, Pozzuoli, Italy.
Maria Rosaria NugnesUrology Complex Unit-ASL Napoli 2 Nord "Santa Maria delle Grazie" Hospital, Pozzuoli, Italy.
Giovanni Di LauroUrology Complex Unit-ASL Napoli 2 Nord "Santa Maria delle Grazie" Hospital, Pozzuoli, Italy.
Francesco TramaUrology Complex Unit-ASL Napoli 2 Nord "Santa Maria delle Grazie" Hospital, Pozzuoli, Italy.
Ospedale Santa Maria · ITUniversity of Campania "Luigi Vanvitelli" · ITUniversity of Verona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo evaluate the 10-year functional outcomes (primary) and frequency and predictors of BPH surgical retreatment (secondary) after ThuLEP. MATERIALS AND

methodsA single-center retrospective analysis of consecutive patients undergoing ThuLEP between 2010 and 2013 was performed. Inclusion criteria were: age ≥ 40 years, prostate volume (PV) ≥ 80 mL, International Prostate Symptom Score (IPSS)-Total score ≥ 8 points. IPSS-Total score was the primary outcome, and BPH surgical retreatment rate was the secondary outcome. Paired t-test, McNemar test, and Wilcoxon signed-rank test were used to compare variables. Logistic regression analysis was performed to evaluate predictors of surgical retreatment.

resultsA total of 410 patients with a mean ±SD age of 63.9 ± 9.7 years and a PV of 115.6 ± 28.6 mL were included. Mean ±SD follow-up was 108.2 ± 29.6 months. IPSS-Total score was significantly improved at 1 year compared to baseline (23.3 ± 4.7 vs. 10.3 ± 3.8; p<0.001). It was similar after 5 years (10.5 ± 3.6 vs. 10.7 ± 5.0; p=0.161), with a significant worsening at 10 years (10.3 ±4.8 vs. 13.8 ±4.5; p=0.042) but remaining statistically and clinically better than baseline (13.8 ±4.5 vs. 22.1 ±4.3; p<0.001). After 10 years, 21 (5.9%) patients had undergone BPH reoperation. Baseline PV (adjusted OR 1.27, 95% CI 1.09-1.41; p<0.001) and time from BPH surgery (adjusted OR 1.32, 95% CI 1.15-1.43; p<0.001) were predictors of BPH surgical retreatment.

conclusionsThuLEP is associated with optimal functional outcomes and a low frequency of BPH surgical retreatment in the long-term. Baseline PV and time from surgery were predictors of BPH reoperation.

Indexed as

Lasers, Solid-StateLaser TherapyProstatic HyperplasiaAdultAgedFollow-Up StudiesHumansMaleMiddle AgedProstateRetreatmentRetrospective StudiesThuliumTreatment OutcomeThuliumProstatic HyperplasiaSurgical Procedures, OperativeThulium

Identifiers

PMID38446905
PMCPMC11152334
OpenAlexW4394761876

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.