Evidence map›Paper›PMID 38452133›Full record

Trial reportThe journals of gerontology. Series A, Biological sciences and medical sciences2024

Effects of Multicomponent Home-Based Intervention on Muscle Composition, Fitness, and Bone Density After Hip Fracture.

Alice S Ryan, Brock A Beamer, Ann L Gruber-Baldini, Rebecca L Craik, Justine Golden, Jack Guralnik, Marc C Hochberg, Kathleen K Mangione, Denise Orwig, Alan M Rathbun and 1 more

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The journals of gerontology. Series A, Biological sciences and medical sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01783704 (Improving Community Ambulation After Hip Fracture), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01783704 nacompletednot on this map

Improving Community Ambulation After Hip Fracture

TypeinterventionalSponsorUniversity of Maryland, BaltimoreRan2013 to 2017Enrolled210ConditionsHip FractureArmsNutrition, PUSH, PULSE
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Alice S RyanDepartment of Medicine, Division of Gerontology, Geriatrics and Palliative Medicine, Baltimore VAMC, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Brock A BeamerDepartment of Medicine, Division of Gerontology, Geriatrics and Palliative Medicine, Baltimore VAMC, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Ann L Gruber-BaldiniDivision of Gerontology, Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-0190-1973
Rebecca L CraikDepartment of Physical Therapy, College of Health Sciences, Arcadia University, Glenside, Pennsylvania, USA.
Justine GoldenDivision of Gerontology, Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Jack GuralnikDivision of Gerontology, Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Marc C HochbergDepartment of Medicine, UMSOM and Medical Care Clinical Center, VA Maryland Health Care System, Baltimore, Maryland, USA.
Kathleen K MangioneDepartment of Physical Therapy, College of Health Sciences, Arcadia University, Glenside, Pennsylvania, USA.
Denise OrwigDivision of Gerontology, Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Alan M RathbunDivision of Gerontology, Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Jay MagazinerDivision of Gerontology, Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.
University of Maryland, Baltimore · USArcadia University · USVA Maryland Health Care System · US

Funding

University of Maryland Claude D. Pepper Older Americans Independence Center (UM-OAIC)P30AG028747 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI ALICE S. RYAN · 2006 to 2026
$28.9M
Sequelae of Hip Fracture in Men: An Epidemiologic StudyR37AG009901 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI MAGAZINER, JAY · 1992 to 2018
$11.3M
Community Ambulation Following Hip FractureR01AG035009 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI MAGAZINER, JAY · 2010 to 2016
$11.0M
The Epidemiology of Bone Strength and Muscle Composition After Hip Fracture in MeR01AG029315 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI MAGAZINER, JAY · 2007 to 2011
$4.1M
A Feasibility and Pilot Study of Combined Treatment Protocol using Aerobic Exercise and Duloxetine in Older Adults with Symptomatic Knee Osteoarthritis and Comorbid DepressionK01AG064041 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI RATHBUN, ALAN MICHAEL · 2019 to 2023
$619k
Timing And Intensity Of Strengthening After Hip FractureR21HD043269 · NICHD · ARCADIA UNIVERSITY · PI CRAIK, REBECCA LYNN · 2002 to 2003
$316k
RR&D Research Career Scientist Award ApplicationIK6RX003977 · VA · BALTIMORE VA MEDICAL CENTER · PI ALICE S. RYAN · 2022 to 2026
–
NIA NIH HHS K01 AG064041NIA NIH HHS P30 AG028747NIA NIH HHS R01 AG029315NIA NIH HHS R01 AG035009NIA NIH HHS R37 AG009901NICHD NIH HHS R21 HD043269NIH HHS R01 AG035009RRD VA IK6 RX003977
6 · The paper itself

Abstract

backgroundMechanistic factors on the pathway to improving independent ambulatory ability among hip fracture patients by a multicomponent home-based physical therapy intervention that emphasized aerobic, strength, balance, and functional training are unknown. The aim of this study was to determine the effects of 2 different home-based physical therapy programs on muscle area and attenuation (reflects muscle density) of the lower extremities, bone mineral density (BMD), and aerobic capacity.

methodsRandomized controlled trial of home-based 16 weeks of strength, endurance, balance, and function exercises (PUSH, n = 19) compared to seated active range-of-motion exercises and transcutaneous electrical neurostimulation (PULSE, n = 18) in community-dwelling adults >60 years of age within 26 weeks of hip fracture.

resultsIn PUSH and PULSE groups combined, the fractured leg had lower muscle area and muscle attenuation and higher subcutaneous fat than the nonfractured leg (p < .001) at baseline. At 16 weeks, mean muscle area of the fractured leg was higher in the PUSH than PULSE group (p = .04). Changes in muscle area were not significantly different when compared to the comparative PULSE group. There was a clinically relevant difference in change in femoral neck BMD between groups (p = .05) that showed an increase after PULSE and decrease after PUSH. There were generally no between-group differences in mean VO2peak tests at 16-week follow-up, except the PUSH group reached a higher max incline (p = .04).

conclusionsThe treatment effects of a multicomponent home-based physical therapy intervention on muscle composition, BMD, and aerobic capacity were not significantly different than an active control intervention in older adults recovering from hip fracture.

trial registrationClinicalTrials.gov Identifier: NCT01783704.

Indexed as

Bone DensityHip FracturesAgedExerciseExercise TherapyHumansMusclesAerobic capacityAgingBone densityHip fractureMuscle composition

Identifiers

PMID38452133
PMCPMC11025556
OpenAlexW4392544836

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.