Evidence map›Paper›PMID 38455289›Full record

ArticleFrontiers in epidemiology2022

Blood oxygen saturation is lower in persons with pre-diabetes and screen-detected diabetes compared with non-diabetic individuals: A population-based study of the Lolland-Falster Health Study cohort.

Jens Christian Laursen, Randi Jepsen, Neda Esmailzadeh Bruun-Rasmussen, Marie Frimodt-Møller, Marit Eika Jørgensen, Peter Rossing, Christian Stevns Hansen

Open access · diamondAbstract read
In one paragraph

Article in Frontiers in epidemiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Reframing SpOFrontiers in physiology · 2025
    Review
  3. Sleep-disordered breathing increases mortality in patients with diabetes.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Observational
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Jens Christian LaursenComplications Research, Steno Diabetes Center Copenhagen, Herlev, Denmark.
Randi JepsenCenter for Epidemiological Research, Nykøbing Falster Hospital, Nykøbing Falster, Denmark.
Neda Esmailzadeh Bruun-RasmussenCenter for Epidemiological Research, Nykøbing Falster Hospital, Nykøbing Falster, Denmark.
Marie Frimodt-MøllerComplications Research, Steno Diabetes Center Copenhagen, Herlev, Denmark.
Marit Eika JørgensenSteno Diabetes Center Greenland, Nuuk, Greenland.
Peter RossingComplications Research, Steno Diabetes Center Copenhagen, Herlev, Denmark.
Christian Stevns HansenComplications Research, Steno Diabetes Center Copenhagen, Herlev, Denmark.
Steno Diabetes Center · DKSjællands Universitetshospital, Nykøbing F. · DKIlisimatusarfik · GLUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: Low blood oxygen saturation is associated with increased mortality and persons with diabetes have sub-clinical hypoxemia. We aimed to confirm the presence of sub-clinical hypoxemia in pre-diabetes, screen-detected diabetes and known diabetes. Methods: Pre-diabetes was defined as hemoglobin A1C (HbA Results: The study included 829 adults (≥18 years) with diabetes (713 (86%) with known diabetes; 116 (14%) with screen-detected diabetes) and 12,747 without diabetes (11,981 (94%) healthy controls; 766 (6%) with pre-diabetes). Mean (95% CI) blood oxygen saturation was 96.3% (96.3% to 96.4%) in diabetes which was lower than in non-diabetes [97.3% (97.2-97.3%)] after adjustment for age, gender, and smoking ( Conclusions: Persons with pre-diabetes and screen-detected diabetes have sub-clinical hypoxemia, which is associated with albuminuria.

Indexed as

albuminuriahypoxiamicrovascular complicationspre-diabetestype 2 diabetes

Identifiers

PMID38455289
PMCPMC10910962
OpenAlexW4304890501

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.