Evidence mapPaperPMID 38456597Full record

ReviewJournal of diabetes investigation2024

Cancer biology in diabetes update: Focusing on antidiabetic drugs.

Emi Kawakita, Keizo Kanasaki

Abstract readReview
In one paragraph

Review in Journal of diabetes investigation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Diabetes and cancer: therapeutic implications.Cardio-oncology (London, England) · 2026
    Review
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Emi KawakitaDepartment of Internal Medicine 1, Faculty of Medicine, Shimane University, Izumo, Japan.ORCID https://orcid.org/0000-0002-5551-8267
Keizo KanasakiDepartment of Internal Medicine 1, Faculty of Medicine, Shimane University, Izumo, Japan.ORCID https://orcid.org/0000-0002-9563-502X

Funding

Japan Diabetes SocietyJapan Society for the Promotion of Science 22K08330Japan Society for the Promotion of Science 23K14567Ministry of Health Labour and Welfare 202112004A
6 · The paper itself

Abstract

The association of type 2 diabetes with certain cancer risk has been of great interest for years. However, the effect of diabetic medications on cancer development is not fully understood. Prospective clinical trials have not elucidated the long-term influence of hypoglycemic drugs on cancer incidence and the safety for cancer-bearing patients with diabetes, whereas numerous preclinical studies have shown that antidiabetic drugs could have an impact on carcinogenesis processes beyond the glycemic control effect. Because there is no evidence of the safety profile of antidiabetic agents on cancer biology, careful consideration would be required when prescribing any medicines to patients with diabetes and existing tumor. In this review, we discuss the potential influence of each diabetes therapy in cancer 'initiation', 'promotion' and 'progression'.

Indexed as

Diabetes Mellitus, Type 2Hypoglycemic AgentsNeoplasmsAnimalsHumansHypoglycemic AgentsAntidiabetic drugsCancerDiabetes

Identifiers

PMID38456597
PMCPMC11060166

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.