Evidence map›Paper›PMID 38461321›Full record

ArticleCommunications biology2024

Dietary restriction modulates ultradian rhythms and autocorrelation properties in mice behavior.

Jackelyn Melissa Kembro, Ana Georgina Flesia, Victoria América Acosta-Rodríguez, Joseph S Takahashi, Paula Sofía Nieto

Abstract read
In one paragraph

Article in Communications biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jackelyn Melissa KembroUniversidad Nacional de Córdoba (UNC), Facultad de Ciencias Exactas, Físicas y Naturales, Instituto de Ciencia y Tecnología de los Alimentos (ICTA) and Departamento de Química, Cátedra de Química Biológica, Córdoba, Córdoba, X5000HUA, Argentina.ORCID 0000-0003-1127-8975
Ana Georgina FlesiaUniversidad Nacional de Córdoba, Facultad de Matemática, Astronomía, Física y Computación, Córdoba, Córdoba, X5000HUA, Argentina.
Victoria América Acosta-RodríguezDepartment of Neuroscience, Peter O'Donnell Jr. Brain Institute, University of Texas Southwestern Medical Center, Dallas, TX, 75390-9111, USA.ORCID 0000-0002-4818-0667
Joseph S TakahashiDepartment of Neuroscience, Peter O'Donnell Jr. Brain Institute, University of Texas Southwestern Medical Center, Dallas, TX, 75390-9111, USA.ORCID 0000-0003-0384-8878
Paula Sofía NietoUniversidad Nacional de Córdoba, Facultad de Matemática, Astronomía, Física y Computación, Córdoba, Córdoba, X5000HUA, Argentina. paula.nieto@unc.edu.ar.ORCID 0009-0007-2600-1684

Funding

Molecular mechanisms of mammalian circadian clock function - Renewal - 1R35GM127122 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI Carla B. Green · 2018 to 2026
$6.0M
Understanding the role of circadian clocks on healthy longevityZIAAG000589 · NIA · NATIONAL INSTITUTE ON AGING · PI ACOSTA-RODRÍGUEZ, VICTORIA · 2024 to 2025
$1.9M
Transcriptional Architecture and Chromatin Landscape of Circadian Clocks in AgingR01AG045795 · NIA · UT SOUTHWESTERN MEDICAL CENTER · PI GREEN, CARLA B., TAKAHASHI, JOSEPH S · 2013 to 2017
$1.5M
Circadian Rhythms and LifespanR56AG072736 · NIA · UT SOUTHWESTERN MEDICAL CENTER · PI GREEN, CARLA B., TAKAHASHI, JOSEPH S · 2021 to 2021
$333k
Elucidating the mechanism for malaria rhythmicity: an underlying circadian clock of the parasiteK99GM132557 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI RIJO-FERREIRA, FILIPA · 2019 to 2021
$122k
NIA NIH HHS R01 AG045795NIA NIH HHS R56 AG072736NIGMS NIH HHS K99 GM132557NIGMS NIH HHS R35 GM127122
6 · The paper itself

Abstract

Animal behavior emerges from integration of many processes with different spatial and temporal scales. Dynamical behavioral patterns, including daily and ultradian rhythms and the dynamical microstructure of behavior (i.e., autocorrelations properties), can be differentially affected by external cues. Identifying these patterns is important for understanding how organisms adapt to their environment, yet unbiased methods to quantify dynamical changes over multiple temporal scales are lacking. Herein, we combine a wavelet approach with Detrended Fluctuation Analysis to identify behavioral patterns and evaluate changes over 42-days in mice subjected to different dietary restriction paradigms. We show that feeding restriction alters dynamical patterns: not only are daily rhythms modulated but also the presence, phase and/or strength of ~12h-rhythms, as well as the nature of autocorrelation properties of feed-intake and wheel running behaviors. These results highlight the underlying complexity of behavioral architecture and offer insights into the multi-scale impact of feeding habits on physiology.

Indexed as

Ultradian RhythmAgricultureAnimalsBehavior, AnimalEatingMiceMotor Activity

Identifiers

PMID38461321
PMCPMC10925031

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.