Evidence map›Paper›PMID 38464489›Full record

ArticleOpen forum infectious diseases2024

Do Infectious Diseases After Kidney Retransplantation Differ From Those After First Kidney Transplantation?

Katharina Kusejko, Dionysios Neofytos, Christian van Delden, Hans H Hirsch, Pascal Meylan, Katia Boggian, Cedric Hirzel, Christian Garzoni, Daniel Sidler, Aurelia Schnyder and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open forum infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Katharina KusejkoDepartment of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland.ORCID https://orcid.org/0000-0002-4638-1940
Dionysios NeofytosDivision of Infectious Diseases, University Hospital of Geneva, Geneva, Switzerland.ORCID https://orcid.org/0000-0001-6970-2869
Christian van DeldenDivision of Infectious Diseases, University Hospital of Geneva, Geneva, Switzerland.
Hans H HirschTransplantation and Clinical Virology, Department of Biomedicine, University of Basel, Basel, Switzerland.
Pascal MeylanFaculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.
Katia BoggianDivision of Infectious Diseases, Infection Prevention and Travel Medicine, Cantonal Hospital of St Gallen, St Gallen, Switzerland.
Cedric HirzelDepartment of Infectious Diseases, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Christian GarzoniDepartment of Infectious Diseases, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Daniel SidlerDivision of Nephrology and Hypertension, Inselspital, Bern University Hospital, Bern, Switzerland.
Aurelia SchnyderClinic for Nephrology, Cantonal Hospital of St Gallen, St Gallen, Switzerland.
Stefan SchaubClinic for Transplantation Immunology and Nephrology, University Hospital Basel, Basel, Switzerland.
Déla GolshayanTransplantation Center, Lausanne University Hospital, Lausanne, Switzerland.
Fadi HaidarDivision of Nephrology, Department of Medicine, University Hospital of Geneva, Geneva, Switzerland.
Marco BonaniDivision of Nephrology, University Hospital Zurich, Zurich, Switzerland.
Roger D KouyosDepartment of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland.
Nicolas J MuellerDepartment of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland.
Peter W SchreiberDepartment of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland.
Swiss Transplant Cohort Study

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Infectious diseases (IDs) are highly relevant after solid organ transplantation in terms of morbidity and mortality, being among the most common causes of death. Patients undergoing kidney retransplantation (re-K-Tx) have been already receiving immunosuppressive therapy over a prolonged period, potentially facilitating subsequent infections. Comparing ID events after re-K-Tx and first kidney transplantation (f-K-Tx) can delineate patterns and risks of ID events associated with prolonged immunosuppression. Methods: We included adult patients with records on f-K-Tx and re-K-Tx in the Swiss Transplant Cohort Study. We analyzed ID events after f-K-Tx and re-K-Tx within the same patients and compared infection rates, causative pathogens, and infection sites. Recurrent time-to-event analyses were performed for comparison of infection rates. Results: A total of 59 patients with a median age of 47 years (range, 18-73) were included. Overall, 312 ID events in 52 patients occurred. In multivariable recurrent event modeling, the rate of ID events was significantly lower after re-K-Tx (hazard ratio, 0.70; Conclusions: ID events were less frequent after re-K-Tx. Affected sites differed significantly after f-K-Tx vs re-K-Tx.

Indexed as

infectionskidney retransplantationorgan allocation

Identifiers

PMID38464489
PMCPMC10923290

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.