Evidence map›Paper›PMID 38464668›Full record

ReviewBiomicrofluidics2024

Engineering models of head and neck and oral cancers on-a-chip.

Mauricio Goncalves da Costa Sousa, Sofia M Vignolo, Cristiane Miranda Franca, Jared Mereness, May Anny Alves Fraga, Alice Corrêa Silva-Sousa, Danielle S W Benoit, Luiz Eduardo Bertassoni

Abstract readReview
In one paragraph

Review in Biomicrofluidics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Host-microbe-cancer interactions on-a-chip.Frontiers in bioengineering and biotechnology · 2025
    Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mauricio Goncalves da Costa SousaORCID https://orcid.org/0000-0001-6009-035X
Jared MerenessDepartments of Biomedical Engineering and Dermatology and Center for Musculoskeletal Research, University of Rochester, 601 Elmwood Ave, Rochester, New York 14642, USA.ORCID https://orcid.org/0000-0001-9621-5580
Alice Corrêa Silva-SousaDepartment of Restorative Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo. Av. do Café - Subsetor Oeste-11 (N-11), Ribeirão Preto, SP, 14040-904, Brazil.ORCID https://orcid.org/0000-0002-9931-0935

Funding

Training in Environment ToxicologyT32ES007026 · NIEHS · UNIVERSITY OF ROCHESTER · PI Alison Elder, Marissa Sobolewski Terry · 1985 to 2026
$20.2M
Microengineering vascularized and innervated bone-like scaffolds as an alternative to autologous bone graftsR01DE029553 · NIDCR · OREGON HEALTH & SCIENCE UNIVERSITY · PI BERTASSONI, LUIZ EDUARDO · 2021 to 2025
$3.0M
Engineered salivary gland tissue chips (Administrative Supplement)UH3DE027695 · NIDCR · UNIVERSITY OF ROCHESTER · PI BENOIT, DANIELLE S., DELOUISE, LISA A · 2019 to 2021
$3.0M
Microengineering the Dental Pulp Vascular Microenvironment_Diversity SupplementR01DE026170 · NIDCR · OREGON HEALTH & SCIENCE UNIVERSITY · PI BERTASSONI, LUIZ EDUARDO · 2016 to 2020
$2.5M
PORT (Portland Oral health Research Training)T90DE030859 · NIDCR · OREGON HEALTH & SCIENCE UNIVERSITY · PI WU, HUI · 2021 to 2025
$2.1M
Engineered salivary gland tissue chipsUG3DE027695 · NIDCR · UNIVERSITY OF ROCHESTER · PI BENOIT, DANIELLE S., DELOUISE, LISA A · 2017 to 2018
$1.5M
PORT (Portland Oral health Research Training)R90DE031533 · NIDCR · OREGON HEALTH & SCIENCE UNIVERSITY · PI WU, HUI · 2021 to 2025
$821k
Engineering Immunomodulatory Scaffolds for Dental Pulp RegenerationK01DE030484 · NIDCR · OREGON HEALTH & SCIENCE UNIVERSITY · PI MIRANDA FRANCA, CRISTIANE · 2022 to 2024
$464k
An organ-on-a-chip model system to study prostate cancer metastasis into vascularized boneR21CA263860 · NCI · OREGON HEALTH & SCIENCE UNIVERSITY · PI BERTASSONI, LUIZ EDUARDO, MORAN, AMY E · 2022 to 2023
$392k
NCI NIH HHS R21 CA263860NIDCR NIH HHS K01 DE030484NIDCR NIH HHS R01 DE026170NIDCR NIH HHS R01 DE029553NIDCR NIH HHS R90 DE031533NIDCR NIH HHS T90 DE030859NIDCR NIH HHS UG3 DE027695NIDCR NIH HHS UH3 DE027695NIEHS NIH HHS T32 ES007026
6 · The paper itself

Abstract

Head and neck cancers (HNCs) rank as the sixth most common cancer globally and result in over 450 000 deaths annually. Despite considerable advancements in diagnostics and treatment, the 5-year survival rate for most types of HNCs remains below 50%. Poor prognoses are often attributed to tumor heterogeneity, drug resistance, and immunosuppression. These characteristics are difficult to replicate using

Identifiers

PMID38464668
PMCPMC10919958

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.