Evidence map›Paper›PMID 38464864›Full record

ArticleNeurophotonics2024

Validation of the Openwater wearable optical system: cerebral hemodynamic monitoring during a breath-hold maneuver.

Christopher G Favilla, Sarah Carter, Brad Hartl, Rebecca Gitlevich, Michael T Mullen, Arjun G Yodh, Wesley B Baker, Soren Konecky

Abstract read
In one paragraph

Article in Neurophotonics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Observational
  2. Article
  3. Article
  4. Article
  5. Building and Sustaining Open-Source Medical Device Projects.IEEE transactions on bio-medical engineering · 2025
    Review
  6. Article
  7. Observational
  8. Article
  9. Article
  10. Article
  11. Pre-Hospital Stroke Care beyond the MSU.Current neurology and neuroscience reports · 2024
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Validation of the Linearity in Image Reconstruction Methods for Speckle Contrast Optical Tomography.IEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics Society
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Christopher G FavillaUniversity of Pennsylvania, Department of Neurology, Philadelphia, Pennsylvania, United States.ORCID https://orcid.org/0000-0003-0871-9549
Sarah CarterUniversity of Pennsylvania, Department of Neurology, Philadelphia, Pennsylvania, United States.
Brad HartlOpenwater, San Francisco, California, United States.ORCID https://orcid.org/0000-0003-4252-4745
Rebecca GitlevichUniversity of Pennsylvania, Department of Neurology, Philadelphia, Pennsylvania, United States.
Michael T MullenTemple University, Department of Neurology, Philadelphia, Pennsylvania, United States.
Arjun G YodhUniversity of Pennsylvania, Department of Physics and Astronomy, Philadelphia, Pennsylvania, United States.ORCID https://orcid.org/0000-0003-4744-2706
Wesley B BakerChildren's Hospital of Philadelphia, Department of Neurology, Philadelphia, Pennsylvania, United States.ORCID https://orcid.org/0000-0002-3025-6061
Soren KoneckyOpenwater, San Francisco, California, United States.

Funding

Training and DisseminationP41EB015893 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI REDDY, RAVINDER · 2012 to 2019
$11.3M
Optical Monitoring of Cerebral Hemodynamics during Mechanical ThrombectomyK23NS110993 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI FAVILLA, CHRISTOPHER G. · 2019 to 2023
$1.0M
NIBIB NIH HHS P41 EB015893NINDS NIH HHS K23 NS110993
6 · The paper itself

Abstract

Significance: Bedside cerebral blood flow (CBF) monitoring has the potential to inform and improve care for acute neurologic diseases, but technical challenges limit the use of existing techniques in clinical practice. Aim: Here, we validate the Openwater optical system, a novel wearable headset that uses laser speckle contrast to monitor microvascular hemodynamics. Approach: We monitored 25 healthy adults with the Openwater system and concurrent transcranial Doppler (TCD) while performing a breath-hold maneuver to increase CBF. Relative blood flow (rBF) was derived from changes in speckle contrast, and relative blood volume (rBV) was derived from changes in speckle average intensity. Results: A strong correlation was observed between beat-to-beat optical rBF and TCD-measured cerebral blood flow velocity (CBFv), Conclusions: This first

Indexed as

biomedical opticsbreath-hold indexcerebral blood flowcerebral hemodynamicslaser speckle contrast

Identifiers

PMID38464864
PMCPMC10923543

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.