Evidence map›Paper›PMID 38465063›Full record

ArticleCureus2024

Challenging Case of Anaplastic Thyroid Cancer With Unusual Clinical and Histological Features: A Diagnostic Dilemma With Undifferentiated Pleomorphic Sarcoma.

Ali Alkhlaifat, Laith Albudour, Mohammad Buwaitel, Ra'ad Alomari, Alia Hajjat, Khaled Helael, Faris Abu Za'nouneh

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ali AlkhlaifatDepartment of Surgery, Royal Medical Services, Amman, JOR.
Laith AlbudourDepartment of Surgery, Royal Medical Services, Amman, JOR.
Mohammad BuwaitelDepartment of Surgery, Royal Medical Services, Amman, JOR.
Ra'ad AlomariDepartment of Surgery, Royal Medical Services, Amman, JOR.
Alia HajjatDepartment of Pathology, Royal Medical Services, Amman, JOR.
Khaled HelaelDepartment of Surgery, Royal Medical Services, Amman, JOR.
Faris Abu Za'nounehDepartment of Internal Medicine, Jordan University of Science and Technology, Irbid, JOR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thyroid cancer is a common malignancy worldwide, and its incidence is increasing rapidly, especially in women. In the majority of cases, it presents solely with a palpable neck swelling. Less commonly, the disease manifests with symptoms of advanced stages, such as superior vena cava (SVC) obstruction and indications of recurrent laryngeal nerve invasion. Anaplastic thyroid cancer is a rare variant of thyroid cancer and is considered to have one of the poorest prognoses, and its diagnosis and treatment are challenging. On the other hand, undifferentiated pleomorphic sarcoma is a differential diagnosis with many clinical and histological similarities, which can only be confirmed through immunohistochemical studies. We herein report a challenging case of a 69-year-old female patient who presented with obstructive symptoms, diagnosed with anaplastic thyroid cancer exhibiting unusual clinical and histological features.

Indexed as

anaplastic thyroid cancerimmunohistochemical stainthyroid histologytumour markersundifferentiated pleomorphic thyroid sarcoma

Identifiers

PMID38465063
PMCPMC10924440

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.