Evidence map›Paper›PMID 38465216›Full record

ArticleJournal of ginseng research2024

Ginseng root-derived exosome-like nanoparticles protect skin from UV irradiation and oxidative stress by suppressing activator protein-1 signaling and limiting the generation of reactive oxygen species.

Wooram Choi, Jeong Hun Cho, Sang Hee Park, Dong Seon Kim, Hwa Pyoung Lee, Donghyun Kim, Hyun Soo Kim, Ji Hye Kim, Jae Youl Cho

Abstract read
In one paragraph

Article in Journal of ginseng research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed.

  1. Article
  2. Advances in Research onInternational journal of molecular sciences · 2026
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  4. Natural Product-Derived Vesicles in Nanotherapeutics.Journal of extracellular vesicles · 2026
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  9. Ginsenosides fromJournal of ginseng research · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Wooram ChoiDepartment of Integrative Biotechnology, Sungkyunkwan University, Suwon, Republic of Korea.
Jeong Hun ChoResearch and Innovation Center, AMOREPACIFIC, Yongin, Republic of Korea.
Sang Hee ParkDepartment of Biocosmetics, Sungkyunkwan University, Suwon, Republic of Korea.
Dong Seon KimDepartment of Integrative Biotechnology, Sungkyunkwan University, Suwon, Republic of Korea.
Hwa Pyoung LeeDepartment of Integrative Biotechnology, Sungkyunkwan University, Suwon, Republic of Korea.
Donghyun KimResearch and Innovation Center, AMOREPACIFIC, Yongin, Republic of Korea.
Hyun Soo KimResearch and Innovation Center, AMOREPACIFIC, Yongin, Republic of Korea.
Ji Hye KimDepartment of Integrative Biotechnology, Sungkyunkwan University, Suwon, Republic of Korea.
Jae Youl ChoDepartment of Integrative Biotechnology, Sungkyunkwan University, Suwon, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Recently, plant-derived exosome-like nanoparticles (PDENs) have been isolated, and active research was focusing on understanding their properties and functions. In this study, the characteristics and molecular properties of ginseng root-derived exosome-like nanoparticles (GrDENs) were examined in terms of skin protection. Methods: HPLC-MS protocols were used to analyze the ginsenoside contents in GrDENs. To investigate the beneficial effect of GrDENs on skin, HaCaT cells were pre-treated with GrDENs (0-2 × 10 Results: GrDENs contained detectable levels of ginsenosides (Re, Rg1, Rb1, Rf, Rg2 ( Conclusions: This study demonstrates the protective effects of GrDENs against skin damage caused by UV and oxidative stress, providing new insights into beneficial uses of ginseng

Indexed as

AgingGinseng-derived exosome-like nanoparticlesGinsenosidesOxidative stressUV irradiation

Identifiers

PMID38465216
PMCPMC10920011

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.