Evidence map›Paper›PMID 38465804›Full record

ArticlePain practice : the official journal of World Institute of Pain2024

Utilizing a learning health system to capture real-world patient data: Application of the reliable change index to evaluate and improve the outcome of a pain rehabilitation program.

Dokyoung S You, Jeanette L Chong, Sean C Mackey, Heather Poupore-King

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In one paragraph

Article in Pain practice : the official journal of World Institute of Pain, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Dokyoung S YouDepartment of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Palo Alto, California, USA.
Jeanette L ChongDepartment of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Palo Alto, California, USA.
Sean C MackeyDepartment of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Palo Alto, California, USA.
Heather Poupore-KingDepartment of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Palo Alto, California, USA.

Funding

Prognostic biomarkers for high-impact chronic pain: Development and validationR61NS118651 · NINDS · STANFORD UNIVERSITY · PI MACKEY, SEAN C · 2020 to 2020
$7.3M
Effect of pain catastrophizing on prescription opioid cravingK23DA048972 · NIDA · STANFORD UNIVERSITY · PI YOU, DOKYOUNG SOPHIA · 2019 to 2023
$758k
Mentoring in Discovery and Validation of Clinical Chronic Pain BiomarkersK24NS126781 · NINDS · STANFORD UNIVERSITY · PI MACKEY, SEAN C · 2021 to 2021
$324k
NIDA NIH HHS K23 DA048972NINDS NIH HHS K24 NS126781NINDS NIH HHS R61 NS118651
6 · The paper itself

Abstract

BACKGROUND AND

objectivesThe learning healthcare system (LHS) has been developed to integrate patients' clinical data into clinical decisions and improve treatment outcomes. Having little guidance on this integration process, we aim to explain (a) an applicable analytic tool for clinicians to evaluate the clinical outcomes at a group and an individual level and (b) our quality improvement (QI) project, analyzing the outcomes of a new outpatient pain rehabilitation program ("Back-in-Action": BIA) and applying the analysis results to modify our clinical practice.

methodsThrough our LHS (CHOIR; https://choir.stanford.edu), we administered the Pain Catastrophizing Scale (PCS), Chronic Pain Acceptance Questionnaire (CPAQ), and Patient-Reported Outcomes Measures (PROMIS)® before and after BIA. After searching for appropriate analytic tools, we decided to use the Reliable Change Index (RCI) to determine if an observed change in the direction of better (improvement) or worse (deterioration) would be beyond or within the measurement error (no change).

resultsOur RCI calculations revealed that at least a 9-point decrease in the PCS scores and 10-point increase in the CPAQ scores would indicate reliable improvement. RCIs for the PROMIS measures ranged from 5 to 8 T-score points (i.e., 0.5-0.8 SD). When evaluating change scores of the PCS, CPAQ, and PROMIS measures, we found that 94% of patients showed improvement in at least one domain after BIA and 6% showed no reliable improvement.

conclusionsOur QI project revealed RCI as a useful tool to evaluate treatment outcomes at a group and an individual level, and RCI could be incorporated into the LHS to generate a progress report automatically for clinicians. We further explained how clinicians could use RCI results to modify a clinical practice, to improve the outcomes of a pain program, and to develop individualized care plans. Lastly, we suggested future research areas to improve the LHS application in pain practice.

Indexed as

Learning Health SystemPatient Reported Outcome MeasuresAdultCatastrophizationChronic PainFemaleHumansMaleMiddle AgedPain ManagementPain MeasurementQuality ImprovementSurveys and QuestionnairesTreatment Outcomeacceptance and commitment therapycognitive behavioral therapyinterdisciplinary pain rehabilitationlearning healthcare systemphysical therapyreliable change index

Identifiers

PMID38465804
PMCPMC11415933

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.