ArticleMovement disorders clinical practice2024
Functional Tic-Like Behaviors: A Common Comorbidity in Patients with Tourette Syndrome.
Article in Movement disorders clinical practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.
- Emerging therapeutic approaches for Tourette syndrome and other tic disorders - a systematic review of current clinical trials.European child & adolescent psychiatry · 2025Pooled it
- Global bibliometric analysis of Tourette syndrome research (1960-2024): trends, collaborations and emerging themes.Frontiers in neurology · 2025Pooled it
- Tourette syndrome.Nature reviews. Disease primers · 2026Review
- Stereotypes about tourette syndrome and associations with social media use: results from a large-scale german population survey.Scientific reports · 2026Article
- Call for action: misinformation about Tourette syndrome from major media network.European child & adolescent psychiatry · 2026Article
- Digital-Supported Delivery of Behavioural Therapy for Patients with Tic Disorders: A Narrative Review.Brain sciences · 2026Review
- Update on the Pathophysiology and Management of Tics.Current neurology and neuroscience reports · 2026Review
- Long-Term Follow-Up of Patients with Mass Social Media-Induced Illness Presenting with Functional Tic-like Behaviors.Movement disorders clinical practice · 2026Article
- The potential role of aberrant microglial synaptic pruning in the neurodevelopmental pathogenesis of tourette syndrome.Frontiers in neuroscience · 2026Review
- Tic-Talk: Voices on Tourette's Labelling.Movement disorders clinical practice · 2025Article
- Neurodevelopmental Tics with Co-Morbid Functional Tic-like Behaviors: Diagnostic Challenges of a Complex Tourette Syndrome Phenotype.Brain sciences · 2025Article
- Epidemiology of Tourette Syndrome.Brain sciences · 2025Review
- Axial tics in Tourette syndrome and chronic tic disorders.Journal of neurology · 2024Article
- A Critical Examination of the Clinical Diagnosis of Functional Tic-like Behaviors.Movement disorders clinical practice · 2024Review
- Validation and assessment of the self-injurious behavior scale for tic disorders (SIBS-T).Scientific reports · 2024Article
- Functional Tic-like Behaviors: From the COVID-19 Pandemic to the Post-Pandemic Era.Healthcare (Basel, Switzerland) · 2024Review
- What distinguishes patients with mass social media-induced illness presenting with Tourette-like behavior from those with Tourette syndrome? Results of a prospective cohort study.European archives of psychiatry and clinical neuroscience · 2024Article
- Tourette syndrome research highlights from 2023.F1000Research · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundComorbid functional tic-like behaviors (FTB) have been described only rarely in patients with Tourette syndrome (TS).
objectivesWe present the first large sample of patients suffering from TS and FTB to raise awareness of this clinical presentation and to guide how to differentiate one from the other.
methodsWe analyzed clinical data of 71 patients (n = 27 [38.0%] female, mean age: 21.5, range: 11-55) with TS + FTB.
resultsIn the majority of patients, FTB started abruptly on average 15 years after tic onset with "treatment-resistant" complex movements and ("coprophenomena-like") vocalizations preceded by timely related psychological stressors. Psychological evaluation revealed evidence for internal conflicts (79%), emotional dysregulation (56%), and maintaining factors (70%). About one third of patients had a positive history for further medically unexplained symptoms. Compared to a large TS sample (n = 1032), patients with TS + FTB were more likely to be female, and presented significantly more common with "coprophenomena-like" symptoms, atypical influential factors, atypical descriptions of premonitory sensations, and higher rates of comorbid obsessive-compulsive disorder and "self-injurious" behavior.
conclusionsBased on our data it can be assumed that FTB is a common comorbidity in TS, similar to functional overlay in other movement disorders and epilepsy. Before classifying a patient as suffering from treatment-resistant TS, FTB should be ruled out.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.