Evidence map›Paper›PMID 38469637›Full record

ArticleAnnals of laboratory medicine2024

Platelet and Monocyte Microvesicles as Potential Biomarkers of COVID-19 Severity: A Cross-Sectional Analysis.

Nastasya Nunki, Yetti Hernaningsih, Puspa Wardhani, Asih Herawati, Narazah Mohd Yusoff, Emmanuel Jairaj Moses, Bambang Pujo Semedi

Abstract read
In one paragraph

Article in Annals of laboratory medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nastasya NunkiLaboratory Medicine Study Interest, Master Program of Basic Medical Science, Faculty of Medicine, Universitas Airlangga, Surabaya, East Java, Indonesia.ORCID https://orcid.org/0000-0003-3235-4375
Yetti HernaningsihDepartment of Clinical Pathology, Faculty of Medicine, Universitas Airlangga, Dr. Soetomo General Academic Teaching Hospital, Surabaya, East Java, Indonesia.ORCID https://orcid.org/0000-0001-8773-8267
Puspa WardhaniDepartment of Clinical Pathology, Faculty of Medicine, Universitas Airlangga, Dr. Soetomo General Academic Teaching Hospital, Surabaya, East Java, Indonesia.ORCID https://orcid.org/0000-0003-2202-8090
Asih HerawatiClinical Pathology Specialist Program, Faculty of Medicine, Universitas Airlangga, Dr. Soetomo General Academic Teaching Hospital, Surabaya, East Java, Indonesia.ORCID https://orcid.org/0000-0002-0805-0999
Narazah Mohd YusoffDepartment of Clinical Pathology, Faculty of Medicine, Universitas Airlangga, Dr. Soetomo General Academic Teaching Hospital, Surabaya, East Java, Indonesia.ORCID https://orcid.org/0000-0001-6801-2508
Emmanuel Jairaj MosesGenetics Unit, Clinical Diagnostics Lab, Advanced Medical and Dental Institute, Universiti Sains Malaysia, Penang, Malaysia.ORCID https://orcid.org/0000-0003-2939-8473
Bambang Pujo SemediDepartment of Anesthesiology and Reanimation, Faculty of Medicine, Universitas Airlangga, Dr. Soetomo General Academic Teaching Hospital, Surabaya, East Java, Indonesia.ORCID https://orcid.org/0000-0001-8829-1540

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Coronavirus disease (COVID-19) induces inflammation, coagulopathy following platelet and monocyte activation, and fibrinolysis, resulting in elevated D-dimer levels. Activated platelets and monocytes produce microvesicles (MVs). We analyzed the differences in platelet and monocyte MV counts in mild, moderate, and severe COVID-19, as well as their correlation with D-dimer levels. Methods: In this cross-sectional study, blood specimens were collected from 90 COVID-19 patients and analyzed for D-dimers using SYSMEX CS-2500. Platelet MVs (PMVs; PMVCD42b Results: PMV and MMV counts were significantly increased in COVID-19 patients. AnnV Conclusions: PMV PMVCD42b

Indexed as

BiomarkersBlood PlateletsCell-Derived MicroparticlesCOVID-19Fibrin Fibrinogen Degradation ProductsMonocytesSARS-CoV-2Severity of Illness IndexAdultAgedAged, 80 and overCross-Sectional StudiesFemaleHumansMaleMiddle AgedBiomarkersFibrin Fibrinogen Degradation Productsfibrin fragment DAnnexin VCD14CD41aCD42bCOVID-19D-dimerMicrovesicles

Identifiers

PMID38469637
PMCPMC11169774

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.