ArticleThe Plant cell2024
A gradient of the HD-Zip regulator Woolly regulates multicellular trichome morphogenesis in tomato.
Article in The Plant cell, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed, 36 citations in OpenAlex.
- From Model Plants toPlants (Basel, Switzerland) · 2026Review
- A Novel AP2/ERF Transcription Factor Controls Trichome Initiation and Fruit Development in Cucumber.Plant biotechnology journal · 2026Article
- Pan-plantae aquaporin evolution: insights intoHorticulture research · 2026Article
- Review
- The C2H2-type zinc finger protein SlHair5 acts as a regulatory node coordinating trichome development and leaf morphogenesis in tomato.Plant cell reports · 2026Article
- Genome-wide identification of theFrontiers in plant science · 2026Article
- The Genetic Wiring of Plant Trichomes: From Initiation to Fate Specification.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Evolutionary Diversification and Adaptive Evolution Analysis of the Plant HD-Zip IV Subfamily.Genes · 2025Article
- Insight into the genetic network governing long-stalked glandular trichome development in Nicotiana tabacum.Planta · 2025Article
- The role, regulation and application of plant fruit trichomes.Molecular horticulture · 2025Review
- Harbingers of bloom: Identifying the molecular mechanisms controlling fruit bloom formation in cucumbers.The Plant cell · 2025Article
- Wo interacts with SlTCP25 to regulate type I trichome branching in tomato.Horticulture research · 2025Article
- The SlGRAS9-SlMYC1 regulatory module controls glandular trichome formation and modulates resilience to pest in tomato.The Plant journal : for cell and molecular biology · 2025Article
- SlH3 and SlH4 promote multicellular trichome formation and elongation by upregulating woolly in tomato.Horticulture research · 2025Article
- Molecular breeding of tomato: Advances and challenges.Journal of integrative plant biology · 2025Review
- AaMYC3 bridges the regulation of glandular trichome density and artemisinin biosynthesis in Artemisia annua.Plant biotechnology journal · 2025Article
- Light signal regulates endoreduplication and tomato fruit expansion through the SlPIF1a-SlTLFP8-SlCDKB2 module.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Different multicellular trichome types coordinate herbivore mechanosensing and defense in tomato.The Plant cell · 2024Article
- Well prepared: How trichome polymorphism creates an early-warning system against herbivory.The Plant cell · 2024Article
Corrections and comments
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
Abstract
Homeodomain (HD) proteins regulate embryogenesis in animals such as the fruit fly (Drosophila melanogaster), often in a concentration-dependent manner. HD-leucine zipper (Zip) IV family genes are unique to plants and often function in the L1 epidermal cell layer. However, our understanding of the roles of HD-Zip IV family genes in plant morphogenesis is limited. In this study, we investigated the morphogenesis of tomato (Solanum lycopersicum) multicellular trichomes, a type of micro-organ in plants. We found that a gradient of the HD-Zip IV regulator Woolly (Wo) coordinates spatially polarized cell division and cell expansion in multicellular trichomes. Moreover, we identified a TEOSINTE BRANCHED1, CYCLOIDEA, and PROLIFERATING CELL NUCLEAR ANTIGEN BINDING FACTOR (TCP) transcription factor-encoding gene, SlBRANCHED2a (SlBRC2a), as a key downstream target of Wo that regulates the transition from cell division to cell expansion. High levels of Wo promote cell division in apical trichome cells, whereas in basal trichome cells, Wo mediates a negative feedback loop with SlBRC2a that forces basal cells to enter endoreduplication. The restricted high and low activities of Wo pattern the morphogenesis of tomato multicellular trichomes. These findings provide insights into the functions of HD-Zip IV genes during plant morphogenesis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.