Evidence map›Paper›PMID 38472506›Full record

ReviewBasic research in cardiology2024

Pathophysiology and clinical relevance of atrial myopathy.

Michiel R L Tubeeckx, Gilles W De Keulenaer, Hein Heidbuchel, Vincent F M Segers

Abstract readReview
PubMed Publisher
In one paragraph

Review in Basic research in cardiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Histone Deacetylase 6 Controls Atrial Fibrosis and Remodeling in Postinfarction Mice Through the Modulation of Wnt3a/GSK-3β Signaling.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Atrial Cardiomyopathy: From Diagnosis to Treatment.Reviews in cardiovascular medicine · 2025
    Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Michiel R L TubeeckxLaboratory of Physiopharmacology, Universiteitsplein 1, Building T (2nd Floor), 2610, Antwerp, Belgium. michiel.tubeeckx@uantwerpen.be.ORCID 0000-0002-1337-0727
Gilles W De KeulenaerLaboratory of Physiopharmacology, Universiteitsplein 1, Building T (2nd Floor), 2610, Antwerp, Belgium.ORCID 0000-0002-4238-4183
Hein HeidbuchelResearch Group Cardiovascular Diseases, GENCOR, University of Antwerp, Antwerp, Belgium.ORCID 0000-0001-9301-8127
Vincent F M SegersLaboratory of Physiopharmacology, Universiteitsplein 1, Building T (2nd Floor), 2610, Antwerp, Belgium.ORCID 0000-0001-7796-2222

Funding

Fonds Wetenschappelijk Onderzoek 1842219NFonds Wetenschappelijk Onderzoek G021019NFonds Wetenschappelijk Onderzoek G021420NUniversiteit Antwerpen PID36444VLIRUOS 20-VLIR-iBOF-027
6 · The paper itself

Abstract

Atrial myopathy is a condition that consists of electrical, structural, contractile, and autonomic remodeling of the atria and is the substrate for development of atrial fibrillation, the most common arrhythmia. Pathophysiologic mechanisms driving atrial myopathy are inflammation, oxidative stress, atrial stretch, and neurohormonal signals, e.g., angiotensin-II and aldosterone. These mechanisms initiate the structural and functional remodeling of the atrial myocardium. Novel therapeutic strategies are being developed that target the pathophysiologic mechanisms of atrial myopathy. In this review, we will discuss the pathophysiology of atrial myopathy, as well as diagnostic and therapeutic strategies.

Indexed as

Atrial FibrillationAtrial RemodelingMuscular DiseasesClinical RelevanceHeart AtriaHumansMyocardiumAtrial fibrillationAtrial fibrosisAtrial myopathyAtrial substrateRemodeling

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.