Evidence map›Paper›PMID 38472628›Full record

ArticleCerebellum (London, England)2024

Neuronal Nitric Oxide Synthase Regulates Cerebellar Parallel Fiber Slow EPSC in Purkinje Neurons by Modulating STIM1-Gated TRPC3-Containing Channels.

Le Gui, Vasiliki Tellios, Yun-Yan Xiang, Qingping Feng, Wataru Inoue, Wei-Yang Lu

Abstract read
PubMed Publisher
In one paragraph

Article in Cerebellum (London, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Le Gui *Robarts Research Institute, University of Western Ontario, 1151 Richmond Street North, London, ON, N6A 5B7, Canada.
Vasiliki Tellios *Graduate Program of Neuroscience, University of Western Ontario, 1151 Richmond Street North, London, ON, N6A 5B7, Canada.
Yun-Yan XiangRobarts Research Institute, University of Western Ontario, 1151 Richmond Street North, London, ON, N6A 5B7, Canada.
Qingping FengDepartment of Physiology and Pharmacology, University of Western, Ontario1151 Richmond Street North, London, ON, N6A 5B7, Canada.
Wataru InoueRobarts Research Institute, University of Western Ontario, 1151 Richmond Street North, London, ON, N6A 5B7, Canada. winoue@uwo.ca.
Wei-Yang LuRobarts Research Institute, University of Western Ontario, 1151 Richmond Street North, London, ON, N6A 5B7, Canada. wlu53@uwo.ca.
Western University · CA

Funding

CIHR MOP-133504
6 · The paper itself

Abstract

Responding to burst stimulation of parallel fibers (PFs), cerebellar Purkinje neurons (PNs) generate a convolved synaptic response displaying a fast excitatory postsynaptic current (EPSC

Indexed as

CerebellumExcitatory Postsynaptic PotentialsNitric Oxide Synthase Type IPurkinje CellsStromal Interaction Molecule 1TRPC Cation ChannelsAnimalsHEK293 CellsHumansMiceMice, Inbred C57BLMice, KnockoutNitric OxideReceptors, Metabotropic Glutamatemetabotropic glutamate receptor type 1Nitric OxideNitric Oxide Synthase Type INos1 protein, mouseReceptors, Metabotropic GlutamateStim1 protein, mouseStromal Interaction Molecule 1TRPC3 cation channelTRPC Cation ChannelsCerebellumNeuronal nitric oxide synthaseParallel fiberSlow EPSCSTIM1TRPC3

Identifiers

PMID38472628
OpenAlexW4392678758

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.