Evidence map›Paper›PMID 38474151›Full record

ReviewInternational journal of molecular sciences2024

Interactions of Gram-Positive Bacterial Membrane Vesicles and Hosts: Updates and Future Directions.

Giuseppe Sangiorgio, Emanuele Nicitra, Dalida Bivona, Carmelo Bonomo, Paolo Bonacci, Maria Santagati, Nicolò Musso, Dafne Bongiorno, Stefania Stefani

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
7.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Virulence · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Effect of gut bacterial extracellular vesicles on angiogenic potential and vascular integrity: positive and negative aspects.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026
    Review
  7. Article
  8. Review
  9. Review
  10. Microorganisms · 2026
    Article
  11. Article
  12. Recent advances in membrane vesicles ofJournal of oral microbiology · 2026
    Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. Extracellular vesicles of Gram-negative and Gram-positive probiotics.Journal of microbiology (Seoul, Korea) · 2025
    Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Giuseppe SangiorgioDepartment of Biomedical and Biotechnological Sciences (BIOMETEC), University of Catania, 95125 Catania, Italy.ORCID 0009-0006-9260-2915
Emanuele NicitraDepartment of Biomedical and Biotechnological Sciences (BIOMETEC), University of Catania, 95125 Catania, Italy.ORCID 0000-0003-2299-9356
Dalida BivonaDepartment of Biomedical and Biotechnological Sciences (BIOMETEC), University of Catania, 95125 Catania, Italy.ORCID 0000-0002-2448-0227
Carmelo BonomoDepartment of Biomedical and Biotechnological Sciences (BIOMETEC), University of Catania, 95125 Catania, Italy.ORCID 0000-0001-5426-8799
Paolo BonacciDepartment of Biomedical and Biotechnological Sciences (BIOMETEC), University of Catania, 95125 Catania, Italy.ORCID 0000-0002-7305-7433
Maria SantagatiDepartment of Biomedical and Biotechnological Sciences (BIOMETEC), University of Catania, 95125 Catania, Italy.ORCID 0000-0003-1491-4973
Nicolò MussoDepartment of Biomedical and Biotechnological Sciences (BIOMETEC), University of Catania, 95125 Catania, Italy.ORCID 0000-0003-2451-1158
Dafne BongiornoDepartment of Biomedical and Biotechnological Sciences (BIOMETEC), University of Catania, 95125 Catania, Italy.ORCID 0000-0002-8672-0484
Stefania StefaniDepartment of Biomedical and Biotechnological Sciences (BIOMETEC), University of Catania, 95125 Catania, Italy.
University of Catania · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extracellular vesicles (EVs) are lipid bilayers derived from cell membranes, released by both eukaryotic cells and bacteria into the extracellular environment. During production, EVs carry proteins, nucleic acids, and various compounds, which are then released. While Gram-positive bacteria were traditionally thought incapable of producing EVs due to their thick peptidoglycan cell walls, recent studies on membrane vesicles (MVs) in Gram-positive bacteria have revealed their significant role in bacterial physiology and disease progression. This review explores the current understanding of MVs in Gram-positive bacteria, including the characterization of their content and functions, as well as their interactions with host and bacterial cells. It offers a fresh perspective to enhance our comprehension of Gram-positive bacterial EVs.

Indexed as

Extracellular VesiclesGram-Positive BacteriaBacteriaCell MembraneLipid BilayersMembranesLipid BilayersGram-positive bacteriahost–pathogen interactionsmembrane vesicles

Identifiers

PMID38474151
PMCPMC10932020
OpenAlexW4392374509

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.