Evidence mapPaperPMID 38474808Full record

ReviewNutrients2024

Polyphenols Influence the Development of Endometrial Cancer by Modulating the Gut Microbiota.

Ewa Baranowska-Wójcik, Anna Winiarska-Mieczan, Piotr Olcha, Małgorzata Kwiecień, Karolina Jachimowicz-Rogowska, Łukasz Nowakowski, Andrzej Miturski, Krzysztof Gałczyński

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Ewa Baranowska-WójcikDepartment of Biotechnology, Microbiology and Human Nutrition, University of Life Sciences, Skromna Street 8, 20-704 Lublin, Poland.ORCID 0000-0002-2213-9631
Anna Winiarska-MieczanInstitute of Animal Nutrition and Bromatology, Department of Bromatology and Nutrition Physiology, University of Life Sciences in Lublin, Akademicka 13, 20-950 Lublin, Poland.ORCID 0000-0003-1981-7005
Piotr OlchaDepartment of Gynecology and Gynecological Endocrinology, Medical University of Lublin, Aleje Racławickie 23, 20-049 Lublin, Poland.ORCID 0000-0003-0552-2855
Małgorzata KwiecieńInstitute of Animal Nutrition and Bromatology, Department of Bromatology and Nutrition Physiology, University of Life Sciences in Lublin, Akademicka 13, 20-950 Lublin, Poland.ORCID 0000-0002-8047-8682
Karolina Jachimowicz-RogowskaInstitute of Animal Nutrition and Bromatology, Department of Bromatology and Nutrition Physiology, University of Life Sciences in Lublin, Akademicka 13, 20-950 Lublin, Poland.ORCID 0000-0001-7540-813X
Łukasz NowakowskiDepartment of Gynecology, 1st Clinical Military Hospital in Lublin, Al. Raclawickie 23, 20-049 Lublin, Poland.
Andrzej MiturskiDepartment of Gynecology, 1st Clinical Military Hospital in Lublin, Al. Raclawickie 23, 20-049 Lublin, Poland.ORCID 0000-0002-3550-7747
Krzysztof GałczyńskiFaculty of Medical Sciences and Health Sciences, Siedlce University of Natural Sciences and Humanities, Konarskiego 2, 08-110 Siedlce, Poland.ORCID 0000-0002-0267-9868
University of Life Sciences in Lublin · PL1 Military Clinical Hospital with Outpatient Clinic · PLMedical University of Lublin · PLUniversity of Siedlce · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dysbiosis of the microbiota in the gastrointestinal tract can induce the development of gynaecological tumours, particularly in postmenopausal women, by causing DNA damage and alterations in metabolite metabolism. Dysbiosis also complicates cancer treatment by influencing the body's immune response and disrupting the sensitivity to chemotherapy drugs. Therefore, it is crucial to maintain homeostasis in the gut microbiota through the effective use of food components that affect its structure. Recent studies have shown that polyphenols, which are likely to be the most important secondary metabolites produced by plants, exhibit prebiotic properties. They affect the structure of the gut microbiota and the synthesis of metabolites. In this review, we summarise the current state of knowledge, focusing on the impact of polyphenols on the development of gynaecological tumours, particularly endometrial cancer, and emphasising that polyphenol consumption leads to beneficial modifications in the structure of the gut microbiota.

Indexed as

Endometrial NeoplasmsGastrointestinal MicrobiomeGenital Neoplasms, FemaleDysbiosisFemaleHumansPolyphenolsPrebioticsPolyphenolsPrebioticsendometrial cancergut microbiotagynaecological tumourspolyphenolsprebiotics

Identifiers

PMID38474808
PMCPMC10933800
OpenAlexW4392241630

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.