Evidence map›Paper›PMID 38474872›Full record

Trial reportNutrients2024

Effects of Enteric-Coated Formulation of Sodium Bicarbonate on Bicarbonate Absorption and Gastrointestinal Discomfort.

Fang-Lin Jiang, Dong-Ho Jeong, Seon-Ho Eom, Hae-Moon Lee, Bong-Jin Cha, Ju-Seong Park, RyoonKyoung Kwon, Jeong-Yeon Nam, Hyun-Seon Yu, Su-Hak Heo and 2 more

Open access · goldAbstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Fang-Lin JiangNational Traditional Sports Teaching and Research Section of Hunan Province, College of Physical Education, Hunan Normal University, Changsha 410012, China.ORCID 0000-0002-8668-3433
Dong-Ho JeongDepartment of Pharmaceutical Engineering, College of Medical Sciences, Soonchunhyang University, Asan 31538, Republic of Korea.ORCID 0000-0001-8164-2010
Seon-Ho EomDepartment of Sports Medicine, College of Natural Sciences, Soonchunhyang University, Asan 31538, Republic of Korea.ORCID 0000-0002-7771-9027
Hae-Moon LeeCollege of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.
Bong-Jin ChaR&D Center, Jinyang Pharm. Co., Ltd., Seoul 08826, Republic of Korea.
Ju-Seong ParkDepartment of Pharmaceutical Engineering, College of Medical Sciences, Soonchunhyang University, Asan 31538, Republic of Korea.
RyoonKyoung KwonDepartment of Pharmaceutical Engineering, College of Medical Sciences, Soonchunhyang University, Asan 31538, Republic of Korea.ORCID 0000-0001-5421-0028
Jeong-Yeon NamDepartment of Pharmaceutical Engineering, College of Medical Sciences, Soonchunhyang University, Asan 31538, Republic of Korea.
Hyun-Seon YuDepartment of Pharmaceutical Engineering, College of Medical Sciences, Soonchunhyang University, Asan 31538, Republic of Korea.
Su-Hak HeoDepartment of Medicinal Bioscience, Konkuk University, Chungju 27478, Republic of Korea.
Chul-Hyun KimDepartment of Sports Medicine, College of Natural Sciences, Soonchunhyang University, Asan 31538, Republic of Korea.ORCID 0000-0002-5933-2785
Keon-Hyoung SongDepartment of Pharmaceutical Engineering, College of Medical Sciences, Soonchunhyang University, Asan 31538, Republic of Korea.
Soonchunhyang University · KRSeoul National University · KRHunan Normal University · CNKonkuk University · KR

Funding

Hunan Provincial Social Science Fund Project 23YBA153Hunan Provincial Sports Bureau Project Fund Key research project 2023KT010
6 · The paper itself

Abstract

Sodium bicarbonate is used as an ergogenic supplement to enhance people's performances in various exercises. This study aimed to evaluate the effects of intestinal delivery of sodium bicarbonate on bicarbonate absorption and associated side effects in an experimental human trial. After preparing and assessing enteric-coated and uncoated sodium bicarbonate tablet formulations, pharmacokinetic analysis and gastrointestinal symptom tests were performed after oral administration in the human body. The dose required to increase blood bicarbonate concentration over 5 mmol∙L

Indexed as

BicarbonatesSodium BicarbonateAdministration, OralBiological AvailabilityHumansTablets, Enteric-CoatedBicarbonatesSodium BicarbonateTablets, Enteric-Coateddrug deliveryenteric-coated tabletoral administrationpharmacokineticssports supplement

Identifiers

PMID38474872
PMCPMC10933797
OpenAlexW4392471965

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.