Evidence map›Paper›PMID 38477664›Full record

ArticleAmerican journal of physiology. Endocrinology and metabolism2024

The prostaglandin E

Joshua C Neuman, Austin Reuter, Kathryn A Carbajal, Michael D Schaid, Grant Kelly, Kelsey Connors, Cecilia Kaiser, Joshua Krause, Liam D Hurley, Angela Olvera and 4 more

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Endocrinology and metabolism, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Joshua C NeumanResearch Service, William S. Middleton Memorial Veterans Hospital, Madison, Wisconsin, United States.
Austin ReuterResearch Service, William S. Middleton Memorial Veterans Hospital, Madison, Wisconsin, United States.
Kathryn A CarbajalResearch Service, William S. Middleton Memorial Veterans Hospital, Madison, Wisconsin, United States.
Michael D SchaidResearch Service, William S. Middleton Memorial Veterans Hospital, Madison, Wisconsin, United States.
Grant KellyResearch Service, William S. Middleton Memorial Veterans Hospital, Madison, Wisconsin, United States.
Kelsey ConnorsResearch Service, William S. Middleton Memorial Veterans Hospital, Madison, Wisconsin, United States.
Cecilia KaiserResearch Service, William S. Middleton Memorial Veterans Hospital, Madison, Wisconsin, United States.
Joshua KrauseDepartment of Biology, University of Wisconsin-Lacrosse, La Crosse, Wisconsin, United States.
Liam D HurleyResearch Service, William S. Middleton Memorial Veterans Hospital, Madison, Wisconsin, United States.
Angela OlveraResearch Service, William S. Middleton Memorial Veterans Hospital, Madison, Wisconsin, United States.
Dawn Belt DavisResearch Service, William S. Middleton Memorial Veterans Hospital, Madison, Wisconsin, United States.ORCID 0000-0002-0239-4715
Jaclyn A WisinskiDepartment of Biology, University of Wisconsin-Lacrosse, La Crosse, Wisconsin, United States.ORCID 0000-0003-2127-4572
Maureen GannonDivision of Diabetes, Endocrinology, and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, Wisconsin, United States.ORCID 0000-0003-3287-8101
Michelle E KimpleResearch Service, William S. Middleton Memorial Veterans Hospital, Madison, Wisconsin, United States.ORCID 0000-0003-0869-9699
University of Wisconsin–Madison · USUniversity of Wisconsin–La Crosse · USVanderbilt University Medical Center · US

Funding

Biology of Aging and Age-Related Diseases Training GrantT32AG000213 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI Rozalyn M. Anderson, Sanjay Asthana · 1991 to 2026
$9.9M
The role of G protein-dependent and -independent EP3 signaling in beta-cell compensation and diabetesR01DK137505 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI Michelle E Kimple · 2024 to 2026
$1.9M
Molecular Mechanisms of Dysfunctional Prostaglandin Signaling in the Beta-CellR01DK102598 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI KIMPLE, MICHELLE E · 2014 to 2018
$1.7M
Manipulating islet GPCR activity to promote beta cell proliferation and survivalR01DK120626 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI GANNON, MAUREEN A · 2019 to 2022
$1.7M
G Protein Mediated Mechanisms of Beta Cell Death Dysfunction and Decompensation in DiabetesI01BX003700 · VA · WM S. MIDDLETON MEMORIAL VETERANS HOSP · PI KIMPLE, MICHELLE E · 2018 to 2021
–
G protein mediated mechanisms of beta-cell compensation and failure in type 2 diabetesI01BX005804 · VA · WM S. MIDDLETON MEMORIAL VETERANS HOSP · PI Michelle E Kimple · 2023 to 2026
–
Modulating prostaglandin E2 receptor activity to improve pancreatic islet functionI01BX005399 · VA · VETERANS HEALTH ADMINISTRATION · PI GANNON, MAUREEN A · 2022 to 2025
–
BLRD VA I01 BX003700BLRD VA I01 BX005399BLRD VA I01 BX005804NIA NIH HHS T32 AG000213NIDDK NIH HHS R01 DK102598NIDDK NIH HHS R01 DK120626NIDDK NIH HHS R01 DK137505
6 · The paper itself

Abstract

Signaling through prostaglandin E

Indexed as

Diabetes Mellitus, Type 2Glucose IntoleranceInsulin-Secreting CellsAnimalsDiet, High-FatExenatideGlucoseInsulinInsulin SecretionMiceMice, KnockoutObesityProstaglandinsExenatideGlucoseInsulinProstaglandinsbeta cell (β‐cell)G protein-coupled receptorinsulin secretionpancreatic isletprostaglandin

Identifiers

PMID38477664
PMCPMC11376488
OpenAlexW4392749174

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.