ArticleWorld journal of urology2024
Construction and validation of the nomogram predictive model for post-percutaneous nephrolithotomy urinary sepsis.
Article in World journal of urology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.
- Risk prediction models for postoperative complications of urosepsis in patients with upper urinary calculi: a systematic review and meta-analysis.BMC infectious diseases · 2026Pooled it
- Early systemic inflammatory indices and postoperative SIRS after percutaneous nephrolithotomy under spinal versus general anaesthesia: a prospective cohort study.BMC urology · 2026Observational
- Predicting SIRS after PCNL using machine learning: the joint impact of sarcopenia and staghorn stones.World journal of urology · 2026Article
- A parsimonious preoperative prediction model for postoperative sepsis following upper urinary tract calculi surgery.Urolithiasis · 2026Article
- Prediction of infectious complications after supine percutaneous nephrolithotomy: development and internal validation of a multivariable nomogram.Urolithiasis · 2026Article
- Diagnostic value of immune indicators and cytokines in sepsis after percutaneous nephrolithotomy (PCNL).Journal of medical biochemistry · 2026Article
- Systemic inflammatory response syndrome in pediatric urinary tract infections associated with urolithiasis: a retrospective study of risk factors, pathogens, and antimicrobial resistance at two tertiary hospitals.BMC infectious diseases · 2026Article
- A novel preoperative risk score for predicting Urosepsis after percutaneous nephrolithotomy: validation and clinical application.Urolithiasis · 2025Article
- Construction and validation of a nomogram to predict urosepsis in patients with symptomatic ureterolithiasis after ureteroscopic lithotripsy.Urolithiasis · 2025Article
- Risk factors for urosepsis in diabetic patients with renal and ureteral calculi: A retrospective study.World journal of diabetes · 2025Article
- Development and external validation of a nomogram for predicting sepsis following flexible ureteroscopy.European journal of medical research · 2025Observational
- Constructing a machine learning model for systemic infection after kidney stone surgery based on CT values.Scientific reports · 2025Article
- Therapeutic experience and key techniques of tubeless percutaneous nephrolithotomy.Scientific reports · 2025Article
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Authors and funding
9 authors at 2 institutions in 1 country.
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Abstract
objectiveThis study aimed to construct and validate a simple and accurate clinical nomogram for predicting the occurrence of post-percutaneous nephrolithotomy sepsis, aiming to assist urologists in the early identification, warning, and early intervention of urosepsis, and to provide certain evidence-based medicine basis.
methodsThis study included patients who underwent PCNL surgery due to kidney or upper ureteral stones at the Department of Urology, Affiliated Hospital of Zunyi Medical University, from January 2019 to September 2022. This study utilized univariate and multivariate logistic regression analysis to screen and evaluate the risk factors for sepsis and construct a predictive model. An evaluation was performed using the receiver operating characteristic curve, calibration curve, and decision curve analysis curve. All statistical analyses were conducted using R version 4.2.
resultsA total of 946 patients who underwent post-PCNL were included in this study, among whom 69 patients (7.29%) developed post-PCNL urinary sepsis. Multiple-factor logistic regression analysis identified four independent risk factors associated with post-PCNL urinary sepsis, including positive urinary nitrite (OR = 5.9, P < 0.001), positive urine culture (OR = 7.54, P < 0.001), operative time ≥ 120 min (OR = 20.93, P = 0.0052), and stone size ≥ 30 mm (OR = 13.81, P = 0.0015). The nomogram model demonstrated good accuracy with an AUC value of 0.909, and in the validation cohort, the AUC value was 0.922. The calibration curve indicated a better consistency between the predictive line chart and the actual occurrence of post-PCNL urinary sepsis. The decision curve analysis curve showed favorable clinical utility.
conclusionPreoperative positive urine culture, positive urinary nitrite, operative time ≥ 120 min, and stone size ≥ 30 mm are independent risk factors for developing post-PCNL urinary sepsis. The constructed line chart based on these factors effectively assesses the risk of urinary sepsis in patients after PCNL.
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