Evidence mapPaperPMID 38481651Full record

ArticleCanada communicable disease report = Releve des maladies transmissibles au Canada2023

Influenza vaccines may protect against cardiovascular diseases: The evidence is mounting and should be known by the Canadian public health community.

Philippe De Wals, Michaël Desjardins

Open access · diamondAbstract read
In one paragraph

Article in Canada communicable disease report = Releve des maladies transmissibles au Canada, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Does influenza vaccination contribute to the prevention of cardiovascular events? An umbrella review.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2025
    Article
  3. Summary of the National Advisory Committee on Immunization (NACI) Seasonal Influenza Vaccine Statement for 2025-2026.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Philippe De WalsDepartment of Social and Preventive Medicine, Laval University, Québec City, QC.
Michaël DesjardinsDivision of Infectious Diseases, Centre hospitalier de l'Université de Montréal, Montréal, QC.
Centre Hospitalier de l’Université de Montréal · CAInstitut National de Santé Publique · CI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Evidence on the protective effect of influenza vaccines to prevent cardiovascular disease (CVD) is mounting. We identified 28 systematic reviews/meta-analyses on the effect of influenza vaccines on CVD using different research questions, data sources, selection criteria and outcomes. Most results leaned towards a protective effect. Results of recently published experimental and observational studies not included in these reviews were going in the same direction. The evidence is very robust for cardiovascular deaths and nonfatal myocardial infarction in high-risk individuals, but lower for heart failure, arrhythmia, and stroke and also for all outcomes in low-risk adults. There is also limited evidence for pneumococcal polysaccharide vaccines and evidence has to be collected from ongoing trials on respiratory syncytial virus vaccines. Up to now, this effect has not been considered in economic evaluations of influenza vaccines and its inclusion may change CVD results markedly. This effect is not mentioned in the Canadian Immunization Guide and not known by a majority of vaccinators. The objective of this short commentary is to alert the Canadian public health community and to provide information that could be used at the field level to promote the usefulness of influenza vaccines.

Indexed as

cardiovascular diseaseinfluenza infectioninfluenza vaccinepneumonia

Identifiers

PMID38481651
PMCPMC10936748
OpenAlexW4388818414

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.