Evidence map›Paper›PMID 38486387›Full record

ArticleInfectious disorders drug targets2024

Identification of Genes Encoded Toxin-Antitoxin System in

Karthikeyan Sundaram, Leela Kagithakara Vajravelu, Ravichandiran Velayutham, Utpal Mohan

Abstract read
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Article in Infectious disorders drug targets, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Karthikeyan SundaramDepartment of Microbiology, SRM Medical College Hospital and Research Centre, Kattangulathur, Chennai, 603203, Tamilnadu, India.ORCID 0000-0002-2674-9146
Leela Kagithakara VajraveluDepartment of Microbiology, SRM Medical College Hospital and Research Centre, Kattangulathur, Chennai, 603203, Tamilnadu, India.ORCID 0000-0003-3288-1335
Ravichandiran VelayuthamDepartment of Natural Products, NIPER- Kolkata, Bengal chemicals, Chunilal Bhawan, Kankurgachi, Kolkata, 700054, West Bengal, India.ORCID 0000-0001-7820-9486
Utpal MohanDepartment of Medicinal Chemistry, NIPER- Kolkata, Bengal Chemicals, Chunilal Bhawan, Kankurgachi, Kolkata, 700054, West Bengal, India.ORCID 0000-0002-0256-7305
National Institute of Pharmaceutical Education and Research · INSRM Institute of Science and Technology · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe toxin-antitoxin system is a genetic element that is highly present in

aimsThe study aims to demonstrate the genes encoded toxin-antitoxin system in MATERIALS AND

methodsThe pulmonary and extra-pulmonary tuberculosis clinical samples were collected, and smear microscopy (Ziehl-Neelsen staining) was performed for the detection of high bacilli (3+) count, followed by nucleic acid amplification assay. Bacterial culture and growth assay, genomic DNA extraction, and polymerase chain reaction were also carried out.

resultsThe positive PTB and EPTB samples were determined by 3+ in microscopy smear and the total count of tubercle bacilli determined by NAAT assay was 8.0×100

conclusionIt has been found that Rv1044 and Rv1045 are hypothetical proteins with 624 and 882 base pairs belonging to the

Indexed as

Mycobacterium tuberculosisSputumToxin-Antitoxin SystemsAntitoxinsBacterial ProteinsBacterial ToxinsDNA, BacterialFemaleHumansTuberculosisTuberculosis, PulmonaryAntitoxinsBacterial ProteinsBacterial ToxinsDNA, BacterialantitoxinMycobacterium tuberculosispathogenesistoxintoxin-antitoxin systemTuberculosis

Identifiers

PMID38486387
OpenAlexW4393076733

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.