Evidence map›Paper›PMID 38488420›Full record

ArticleSkin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)2024

N95 respirators alter facial skin physiological functions and lipidome composition in health care personnel.

Min Li, Feifei Wang, Meng Tao, Yue Zhang, Ruoxin Pan, Duoduo Gu, Hui Zhong, Yang Xu

Open access · hybridAbstract read
In one paragraph

Article in Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. N95 respirators alter facial skin physiological functions and lipidome composition in health care personnel.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Min LiDepartment of Dermatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Feifei WangYunnan Characteristic Plant Extraction Laboratory, Yunnan Yunke Characteristic Plant Extraction Laboratory Co., Ltd, Kunming, China.
Meng TaoDepartment of Dermatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.ORCID https://orcid.org/0000-0001-5155-1871
Yue ZhangDepartment of Dermatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Ruoxin PanDepartment of Dermatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Duoduo GuDepartment of Dermatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Hui ZhongState Key Laboratory of Natural Medicines, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, China.
Yang XuDepartment of Dermatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.ORCID https://orcid.org/0000-0001-7172-5277
Jiangsu Province Hospital · CNChina Pharmaceutical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDuring the coronavirus disease 2019 pandemic, wearing medical respirators and masks was essential to prevent transmission.

objectiveTo quantify the effects of N95 mask usage by measuring facial skin biophysical characteristics and changes in the lipidome.

methodsSixty healthy volunteers wore N95 respirators for 3 or 6 h. Facial images were acquired and physiological parameters were measured in specific facial areas, before and after mask-wearing. Lipidome analysis was also performed.

resultsAfter N95 respirator usage, facial erythema was observed in both the 3 and 6 h groups. Both sebum secretion and trans-epidermal water loss increased significantly in mask-covered cheeks and chins after 6 h of mask wearing compared with before mask wearing (p < 0.05). Principal component analysis revealed significant differences in lipid composition after mask wearing compared with before. The ceramide subclass NS exhibited a positive correlation with stratum corneum hydration, whereas the AP subclass was negatively correlated with trans-epidermal water loss in the 6 h group.

conclusionProlonged wear of N95 respirators may impair facial skin function and alter lipidome composition.

Indexed as

N95 RespiratorsRespiratory Protective DevicesDelivery of Health CareHumansLipidomicsMasksWaterWaterface maskhealthcare personnellipidome compositionN95skin functionskin physiological parameters

Identifiers

PMID38488420
PMCPMC10941554
OpenAlexW4392882650

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.