Evidence map›Paper›PMID 38492029›Full record

ReviewSkeletal radiology2024

Multimodal positron emission tomography (PET) imaging in non-oncologic musculoskeletal radiology.

Feliks Kogan, Daehyun Yoon, Matthew G Teeter, Abhijit J Chaudhari, Laurel Hales, Marco Barbieri, Garry E Gold, Yael Vainberg, Ananya Goyal, Lauren Watkins

Erratum issuedOpen access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Skeletal radiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Feliks KoganDepartment of Radiology, Stanford University, Stanford, CA, USA. fkogan@stanford.edu.ORCID http://orcid.org/0000-0003-0580-7308
Daehyun YoonDepartment of Radiology, University of California-San Francisco, San Francisco, CA, USA.
Matthew G TeeterDepartment of Medical Biophysics, Western University, London, ON, Canada.
Abhijit J ChaudhariDepartment of Radiology, University of California-Davis, Davis, CA, USA.
Laurel HalesDepartment of Radiology, Stanford University, Stanford, CA, USA.
Marco BarbieriDepartment of Radiology, Stanford University, Stanford, CA, USA.
Garry E GoldDepartment of Radiology, Stanford University, Stanford, CA, USA.
Yael VainbergDepartment of Radiology, Stanford University, Stanford, CA, USA.
Ananya GoyalDepartment of Radiology, Stanford University, Stanford, CA, USA.
Lauren WatkinsDepartment of Radiology, Stanford University, Stanford, CA, USA.
Stanford University · USStanford Medicine · USUniversity of California, Davis · USUniversity of California, San Francisco · USWestern University · CA

Funding

Imaging of Joint Response to Physiological Stress with Age, Sex and in OsteoarthritisR01AR079431 · STANFORD UNIVERSITY · 2025 to 2025
$513k
NCCIH NIH HHS R61 AT012187NCCIH NIH HHS R61AT012187NCI NIH HHS R01 CA206187NCI NIH HHS R01CA206187NIAMS NIH HHS R01 AR074492NIAMS NIH HHS R01AR074492NIAMS NIH HHS R01 AR076088NIAMS NIH HHS R01AR076088NIAMS NIH HHS R01 AR079431NIAMS NIH HHS R01AR079431NIBIB NIH HHS R21 EB030180NIBIB NIH HHS R21EB030180
6 · The paper itself

Abstract

Musculoskeletal (MSK) disorders are associated with large impacts on patient's pain and quality of life. Conventional morphological imaging of tissue structure is limited in its ability to detect pain generators, early MSK disease, and rapidly assess treatment efficacy. Positron emission tomography (PET), which offers unique capabilities to evaluate molecular and metabolic processes, can provide novel information about early pathophysiologic changes that occur before structural or even microstructural changes can be detected. This sensitivity not only makes it a powerful tool for detection and characterization of disease, but also a tool able to rapidly assess the efficacy of therapies. These benefits have garnered more attention to PET imaging of MSK disorders in recent years. In this narrative review, we discuss several applications of multimodal PET imaging in non-oncologic MSK diseases including arthritis, osteoporosis, and sources of pain and inflammation. We also describe technical considerations and recent advancements in technology and radiotracers as well as areas of emerging interest for future applications of multimodal PET imaging of MSK conditions. Overall, we present evidence that the incorporation of PET through multimodal imaging offers an exciting addition to the field of MSK radiology and will likely prove valuable in the transition to an era of precision medicine.

Indexed as

Multimodal ImagingMusculoskeletal DiseasesPositron-Emission TomographyHumansRadiopharmaceuticalsRadiopharmaceuticalsMetabolic imagingMusculoskeletalPETQuantitative imaging

Identifiers

PMID38492029
PMCPMC12778996
OpenAlexW4392880076

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.